A 25 year old male with a history of 7 days skin lesions and last 2 days of fever up to 39°C and diarrhea (up to 10 watery stools, no bloody, no black). He also became fatigued and with the appearance of the rash, his skin lesions became bigger. Personal history is unremarkable. No known allergies. On physical exam, besides big urticarial patches all over the body with the dark rim, I only found one enlarged mobile, non-tender lymph node in the right axilla. The rest of exam was unremarkable. The laboratory analyses showed only elevated CRP (~60) and slightly raised creatinine (117). This didn't look to me as infection. What is your opinion on this case?

A 60 yr diabetic female, presented with such lesions.The lesions are on and off for past 2 years, they appear at the same site (right upper thigh)and resolve completely on their own with hyperpigmentation. They occur again after few days or weeks at the same site. associated with burning sensation, no itching. Kindly opine on the DDs

a lady...aged 62 years ...the skin rashes develped 15 days back...she is a known case of hypothyroidism since last 2 years....taking Thyrox 50 mcg od is this due to thyroid disorder or anything else ...?appetite...good...bowel habit also normal

Pt aged 44 yrs....C/o generalised itching....Since 8 yrs....Daily itching....Taken treatment at many drs no Response and well Known dermatologist treated no response.... Pt is non diabetic/No thyroid problem/No Anaemia/No Scabies/No Liver problem/No renal problem/No Tension or Hysterical/No HIV/No Hbsag positive/No Drug Related Itching/Non HTN/No Food Related Allergy.....Dermatologist given her steroids/Dapsone tabs etc her weight increased but no Symptoms relieved....So pt is Very much Fed up of this along with family members.....No Relief of Itching.....So Challenging One pls share ur Opinions fast......If u feel diagnosis then tell Related Investigation,Treatment and prognosis...Must.

46years female has lesions all over body. Initially it was in both upperlimbs and thigh rgelion. Now spreaded all oover body with severe itching. Patient has no history of dm or htn. Please suggest treatment and tell me diagnosis