?PCOS ?Secondary Amenorrhea
26 yrs F presented with C/O Amenorrhea since 2.5 months, But UPT- Negative. No H/O pain abdomen or any other relevant sign & symptom. PMC- Irregular since last 10 months. Mn attained at 14 yrs of age. MF-2 yrs All Vitals are stable. Not a K/C/O HTN,T2DM & CAD. No H/O any contraception use. No H/O any ectopic pregnancy,abortion & still birth. Pt. taking Tab. Thyroxine 25 mcg OD BBF since last 2 months for newly Diagnosed mild Hypothyroidism. TFT is now WNL. S.Prolactin- WNL. Hb-11.9 g/dl Rest CBC Profile- WNL. LFT-WNL. RFT with SE- WNL. FBS-WNL. USG Pelvic Organs- Normal Study. UPT- negative. HbsAg,HCV,HIV- NR. Kindly comment on the Differential Diagnoses along with Investigation to perform now, if any and line of management & treatment.
Technically it is not yet Secondary amenorrhea which occurs in women who have missed 3 months of periods. Unhealthy Lifestyle factors, and some medications can also cause amenorrhea, but you didn't eloborate upon that. Nutritional deficiencies, particularly Malnutrition may affect how the hypothalamus and pituitary gland function, which can lead to amenorrhea. Is she breastfeeding, by any chance? Having a low body weight can also prevent the hypothalamus and pituitary gland from functioning correctly( functional hypothalamic amenorrhea) Stress can affect hormone levels in the body, and it is another cause of functional hypothalamic amenorrhea. Excessive exercise can also be a cause of functional hypothalamic amenorrhea. Having an eating disorder, such as anorexia or bulimia, may also cause amenorrhea. PCOS, a commonly prevalent but little diagnosed, have an array non specific symptoms including: irregular periods, excessive hair growth, difficulty getting pregnant, weight gain, acne, and not necessarily cystic ovaries on USG PCOS may also lead to hyperandrogenemia, Some investigations with this regard : 1. Testosterone – usually elevated with PCOS. 2. Sex hormone binding globulin (SHBG) – may be reduced in PCOS 3 Anti-Müllerian hormone (AMH) – an increased level is often seen with PCOS.
Technically it is not yet Secondary amenorrhea which occurs in women who have missed 3 months of periods. Unhealthy Lifestyle factors, and some medications can also cause amenorrhea, but you didn't eloborate upon that. Nutritional deficiencies, particularly Malnutrition may affect how the hypothalamus and pituitary gland function, which can lead to amenorrhea. Is she breastfeeding, by any chance? Having a low body weight can also prevent the hypothalamus and pituitary gland from functioning correctly( functional hypothalamic amenorrhea) Stress can affect hormone levels in the body, and it is another cause of functional hypothalamic amenorrhea. Excessive exercise can also be a cause of functional hypothalamic amenorrhea. Having an eating disorder, such as anorexia or bulimia, may also cause amenorrhea. PCOS, a commonly prevalent but little diagnosed, have an array non specific symptoms including: irregular periods, excessive hair growth, difficulty getting pregnant, weight gain, acne, and not necessarily cystic ovaries on USG PCOS may also lead to hyperandrogenemia, Some investigations with this regard : 1. Testosterone – usually elevated with PCOS. 2. Sex hormone binding globulin (SHBG) – may be reduced in PCOS 3 Anti-Müllerian hormone (AMH) – an increased level is often seen with PCOS.
Secondary amenorrhea. Possibly stress, chronic ill ness, hormone therapy, pcos. Needs to evaluate as hormone study. Life style modification. Titration of thyroxine doses every 6 to 8 weeks.
NEED'S.. * ANEMIA PROFILE.. * HORMONAL STUDY.. * USG STUDY.. * GYNECOLOGICAL EXAMINATION..
What about endometrial thickness? S.LH and S. FSH.? Do progesterone challenge test. It should be check either it is negative or positive and then diagnos the Pt step by step. Treat according to diagnosis.
US G abdomen Gynaecologist exam D & C Endometrial Biopsy
Hormonal tests like FSH,LH,S Testosterone should be performed and at the same USG pelvic region should be done to r/o PCOS.
Oval L tab take 5th day after period uvecare syrup next after period 5 th day 3month couse
Irregular Menses kanchanara guggulu, mundi churnam and varun churnam 1/8 th kashayan,ashokarishta.
Usg study. Hormonal evaluation. Experts opinion.
Drug history? Serum prolactin level?
Cases that would interest you
- Login to View the image
Friends today I am discussing about female problem known as amenorrhoea. Amenorrhea (uh-men-o-REE-uh) is the absence of menstruation — one or more missed menstrual periods. Women who have missed at least three menstrual periods in a row have amenorrhea, as do girls who haven't begun menstruation by age 15. The most common cause of amenorrhea is pregnancy. Other causes of amenorrhea include problems with the reproductive organs or with the glands that help regulate hormone levels. Treatment of the underlying condition often resolves amenorrhea. Symptoms The main sign of amenorrhea is the absence of menstrual periods. Depending on the cause of amenorrhea, you might experience other signs or symptoms along with the absence of periods, such as: Milky nipple discharge Hair loss Headache Vision changes Excess facial hair Pelvic pain Acne When to see a doctor Consult your doctor if you've missed at least three menstrual periods in a row, or if you've never had a menstrual period and you're age 15 or older. Female reproductive organs Female reproductive system Amenorrhea can occur for a variety of reasons. Some are normal during the course of a woman's life, while others may be a side effect of medication or a sign of a medical problem. Natural amenorrhea During the normal course of your life, you may experience amenorrhea for natural reasons, such as: Pregnancy Breast-feeding Menopause Contraceptives Some women who take birth control pills may not have periods. Even after stopping oral contraceptives, it may take some time before regular ovulation and menstruation return. Contraceptives that are injected or implanted also may cause amenorrhea, as can some types of intrauterine devices. Medications Certain medications can cause menstrual periods to stop, including some types of: Antipsychotics Cancer chemotherapy Antidepressants Blood pressure drugs Allergy medications Lifestyle factors Sometimes lifestyle factors contribute to amenorrhea, for instance: Low body weight. Excessively low body weight — about 10 percent under normal weight — interrupts many hormonal functions in your body, potentially halting ovulation. Women who have an eating disorder, such as anorexia or bulimia, often stop having periods because of these abnormal hormonal changes. Excessive exercise. Women who participate in activities that require rigorous training, such as ballet, may find their menstrual cycles interrupted. Several factors combine to contribute to the loss of periods in athletes, including low body fat, stress and high energy expenditure. Stress. Mental stress can temporarily alter the functioning of your hypothalamus — an area of your brain that controls the hormones that regulate your menstrual cycle. Ovulation and menstruation may stop as a result. Regular menstrual periods usually resume after your stress decreases. Hormonal imbalance Many types of medical problems can cause hormonal imbalance, including: Polycystic ovary syndrome (PCOS). PCOS causes relatively high and sustained levels of hormones, rather than the fluctuating levels seen in the normal menstrual cycle. Thyroid malfunction. An overactive thyroid gland (hyperthyroidism) or underactive thyroid gland (hypothyroidism) can cause menstrual irregularities, including amenorrhea. Pituitary tumor. A noncancerous (benign) tumor in your pituitary gland can interfere with the hormonal regulation of menstruation. Premature menopause. Menopause usually begins around age 50. But, for some women, the ovarian supply of eggs diminishes before age 40, and menstruation stops. Structural problems Problems with the sexual organs themselves also can cause amenorrhea. Examples include: Uterine scarring. Asherman's syndrome, a condition in which scar tissue builds up in the lining of the uterus, can sometimes occur after a dilation and curettage (D&C), cesarean section or treatment for uterine fibroids. Uterine scarring prevents the normal buildup and shedding of the uterine lining. Lack of reproductive organs. Sometimes problems arise during fetal development that lead to a girl being born without some major part of her reproductive system, such as her uterus, cervix or vagina. Because her reproductive system didn't develop normally, she can't have menstrual cycles. Structural abnormality of the vagina. An obstruction of the vagina may prevent visible menstrual bleeding. A membrane or wall may be present in the vagina that blocks the outflow of blood from the uterus and cervix. Risk factors Factors that may increase your risk of amenorrhea may include: Family history. If other women in your family have experienced amenorrhea, you may have inherited a predisposition for the problem. Eating disorders. If you have an eating disorder, such as anorexia or bulimia, you are at higher risk of developing amenorrhea. Athletic training. Rigorous athletic training can increase your risk of amenorrhea. Complications Complications of amenorrhea may include: Infertility. If you don't ovulate and have menstrual periods, you can't become pregnant. Osteoporosis. If your amenorrhea is caused by low estrogen levels, you may also be at risk of osteoporosis — a weakening of your bones. Homoeopathic medicines There are a variety of homeopathic medicines which can be taken for amenorrhea. That being said, it is important to keep in mind the fact that these medicines should only be made use of after a qualified homeopathic doctor has checked the patient and approved of the medicine. For mothers who have not experienced menses after they started breastfeeding their babies, Sepia is the medicine which is usually recommended. In a similar way, Pinus lamb is recommended for women whose menses are delayed. While these happen to be a couple of very specific or niche medicines, a general medicine for amenorrhea is Pulsatilla. In fact, it is widely considered by doctors to be very effective. When amenorrhea is caused on account of the suppression of menses due to a tumour which is present in the ovaries, most allopathic doctors would be very worried. However, homeopathic doctors would know that there is a solution designed for this very situation, which is known as Apis Mel.
Dr. Rajesh Gupta12 Likes15 Answers - Login to View the image
ENDOMETRIOTIC CYST IN OVARY cured with homeopathic medicines without surgery 2 Large Endometriotic Cyst in Ovary measuring 3.8 x 3.6 x 2.2cms and 2.5 x 2.3 x 1.6cms Cured without surgery with Homeopathic medicines By Dr Deepan P Shah at Dr Shah’s Homeopathy. THE OVARIAN CYSTS RESOLVED IN JUST 60 DAYS First consultation on 10/4/2018 Patient has endometriotic cyst both ovaries, till one year ago she had only on one side. h/o medicines for hypothyroidoism which she had stopped. Prolactin Elevated, h/o occasional oozing of fluid from nipples, only on pressing nipples, patient used to have sensitive nipples even before menarche, this oozing was first noticed when her dermatologist examined nipple and on pressure fuild oozed out. PCOD detected in jan 2014 H/o acne, hairfall Patient also has H/o severe pain in pelvis and lower back in 2017 at that time patient was not even able to sit due to pain, after which she got detected with endometriotic cyst in right ovary then later on left ovary as well. Then patient sarted allopathic hormonal medicines but still she has a constant pain in pelvis but has reduced by 80% Menstrual Functions Menarche at around 14-15 yrs Cycle regular 28 days Initial 10 yrs menstrual bleeding phase used to last for 7 days with heavy flow, her mother used to have similar pattern. Other notable factors Hyperacidity and Constipation since 10 yrs. Patient lost her younger brother 10 yrs ago. Patient follows regular meal pattern. Patient has c/o mild to moderate allergic respiratory affections especially sneezing and rhinorrhoea which Aggravates even on draft of air, needs covering. Lower Backache , pain in Nape of Neck Axillary lymphomegally Renal Stones No Record of Hypertension , Diabetes Mellitus, drug reactions RX PULSATILLA 200 SINGLE DOSE WAS ADMINISTERED AND PATIENT WAS ADMINISTERED SAC LAC Later on after 3 weeks based on her symptoms, she was administered with Conium Mac 200 single dose and left on placebo NOW AFTER ENDOMETRIOTIC CYST HAS BEEN CURED PATIENT IS STILL CONTINUING TREATMENT FOR PCOS WHICH IS ALTOGETHER A DIFFERENT ENTITY Note Reports attached before and after treatment.
Dr. Rajesh Gupta16 Likes18 Answers - Login to View the image
Hello dear Curofians, I would like suggestions regarding following case: 17 yrs old girl presented with irregular cycles since menarchae. M/H : 3 to 4 days once in 45 to 75 days, decreased flow with mild pain. No history of any major illness. On examination, obesity+, 62.5 kg, height 5.1 feet, BP:110/80 mmHg, no galactorrhea. USG normal. No PCOS seen on USG.
Dr. Vasundhara Nanavaty4 Likes20 Answers - Login to View the image
24 year old married obese girl with this classical finding on USG. patient is planning a child. lets discuss management and diagnosis
Dr. Pallavi Mittal4 Likes56 Answers - Login to View the image
29 year female....married with h/o irregular menses....diagonesed with p.c.o.d since 4 year difficulty in conceive ..kindly suggest best treatment.
Dr. Anshu Sharma Sharma8 Likes62 Answers
3 Likes