Is producing ventilators on a mass scale the only solution? If this pandemic goes in community transmission in india, no number of ventilators will be sufficient. No country can arrange this much of number. We have to prepare a better future strategy to deal such situations. There is a sure delay from China to report it. The international flights were banned at a very later stage WHO also declared it a pandemic ya a very latter stage Health sector has always been given less importance by very country compared to defence. Now the world needs to rethink on this issue . A tiny microscopic virus made the whole world helpless and still we human being thinks we are the most advanced developed creature in the evolution.
Hello It will all depend upon how far the isolation is effective In india even 0.5 percent suffering at one point of time figure may 65 lacs cases which may be a most challenging & may be impossible So only effective to control strict home isolation for all May god bless the mother earth
@Dr. Dinesh Gupta @Partha Sarathi Sahana @Pushker Bhomia @Dr. Deepshikha Singh @Amitkumar Bose @Sandeep S
Kindly follow the govt request for Lockdown... Its for all of us... Only we can control this outbreak with our joint effort.... Once this virus spreads to community, our country will perish....
ABSOLUTELY.. TRUE... AGREE. WITH. YOU... DR @. PUSHKER. MEHRA. JI.. THIS. PENDEMIC. Has. EXPOSED.... ...EACH. AND. EVERY... ... SHORTCOMINGS
Why all the developed nations jointly start a new venture of producing ventillators on a mass scale
Make the lockdown a success.Follow Quarantine & save India.
What are the main precautions sir
Dear healers, 1. We cannot deny the fact we have limited equipments and along with the helplessness of daily workers. The efforts by the government are more or less not sufficient. Hopefully, these crises won't rise to the level of suffering as the other nations are facing. 2. According to our literature, fear of disease is more dangerous than the disease itself. By panicking we are getting susceptible to the disease. 3. The lockdown gave us the chance to relax and spend valuable time with our families. Being surrounded with the family always boost one's faith which ultimately lead to increase the immunity. 4. We always been a religious country who gave out best in the crisis. If I think scientifically too..then, navratri rituals in which camphor is used as one of its ingredients which has the properties of disinfectant. 5. This is a war which will be won by unity and its seen by the world in janta curfew on 22th March. Let's be together. 6. It's high time to raise our consciousness to the level of humanity. We are not only the population of 138 crores. Let's see them as 138 crore assets or human resources. So people, let your spirits vibrate high on the frequency where we visualise a healthy nation. Stay home. Stay united.
TO AVOID SUCH A SITUATION AS HAD BEEN REPORTED BY AMERICAN JOURNAL IT'S VERY MUCH IMPORTANT TO FOLLOW THE RULE OF THUMB AND THAT IS PERIOD OF QUARANTINE AND SOCIAL DISTANCE AND FOLLOW UP THE CASES OF COVID 19 TILL THEY BECOME NEGATIVE AND ONE MORE STEP. IS EARLY DETECTION OF THE POSITIVES. BY MASS TESTING..... AND IT SHOULD CONTINUE AND EVEN DOCTORS WHO ARE FAMILY PHYSCIANS SHOULD ATTEND THEIR PATIENTS ON OR VIA TELEPATHY..... AS IF THEY OPEN THEIR CLINICS, THEY WILL BE IN DANGER OF GETTING INFECTED OR THE PATIENTS MAY GET INFECTIONS FROM POSITIVE TO NON POSITIVE..... AND QUACKS, PLEASE DON'T GO. AFTER MONEY THINK ABOUT OUR COUNTRY.... BECAUSE AT PRESENT WE HAVE CONTROL OVER SITUATION IRRESPECTIVE OF VIOLATION OF RULES AND REGULATIONS, BUT ONCE THE SITUATION WENT OUT OF CONTROL THEN YOU WILL BE NO MORE TO THINK THAT WHY IT HAPPENED..... SO ALL ARE REQUESTED TO FOLLOW THE RULE OF QUARANTINE AND SOCIAL DISTANCE..... AND LET'S ALL PRAY FOR THE WELL BEING OF EVERY ONE IRRESPECTIVE OF CASTE, CREED, AND RELIGION..... YOURS SINCERELY......
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x-ray chest of first case of Corona virus pneumonia patient aged 61 years male who died during treatment in WUHAN city of China.Dr. Ramesh Dutt Gautam38 Likes33 Answers
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Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women Background Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were based on information from the general population. Limited data are available for pregnant women with COVID-19 pneumonia. This study aimed to evaluate the clinical characteristics of COVID-19 in pregnancy and the intrauterine vertical transmission potential of COVID-19 infection. Methods Clinical records, laboratory results, and chest CT scans were retrospectively reviewed for nine pregnant women with laboratory-confirmed COVID-19 pneumonia (ie, with maternal throat swab samples that were positive for severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) who were admitted to Zhongnan Hospital of Wuhan University, Wuhan, China, from Jan 20 to Jan 31, 2020. Evidence of intrauterine vertical transmission was assessed by testing for the presence of SARS-CoV-2 in amniotic fluid, cord blood, and neonatal throat swab samples. Breastmilk samples were also collected and tested from patients after the first lactation. Findings All nine patients had a caesarean section in their third trimester. Seven patients presented with a fever. Other symptoms, including cough (in four of nine patients), myalgia (in three), sore throat (in two), and malaise (in two), were also observed. Fetal distress was monitored in two cases. Five of nine patients had lymphopenia (<1·0 × 10⁹ cells per L). Three patients had increased aminotransferase concentrations. None of the patients developed severe COVID-19 pneumonia or died, as of Feb 4, 2020. Nine livebirths were recorded. No neonatal asphyxia was observed in newborn babies. All nine livebirths had a 1-min Apgar score of 8–9 and a 5-min Apgar score of 9–10. Amniotic fluid, cord blood, neonatal throat swab, and breastmilk samples from six patients were tested for SARS-CoV-2, and all samples tested negative for the virus. Interpretation The clinical characteristics of COVID-19 pneumonia in pregnant women were similar to those reported for non-pregnant adult patients who developed COVID-19 pneumonia. Findings from this small group of cases suggest that there is currently no evidence for intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia in late pregnancy. To read more- https://www.sciencedirect.com/science/article/pii/S0140673620303603 Source-sciencedirectDr. Pushker Mehra10 Likes15 Answers
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Therapeutic Potential for Tetracyclines in the Treatment of COVID‐19 This article is protected by copyright. All rights reserved Conflict of interest: The authors declare no conflicts of interest. Currently there is a race against time to identify prophylactic and therapeutic treatments against COVID-19. Until these treatments are developed, tested and mass produced, it might be prudent to look into existing therapies that could be effective against this virus. Based on the available evidence we believe that tetracyclines may be effective agents in the treatment of COVID-19. Tetracyclines (e.g. tetracycline, doxycycline, and minocycline) are highly lipophilic antibiotics that are known to chelate zinc compounds on matrix metalloproteinases (MMPs). Coronaviruses are also known to heavily rely on host MMPs for survival, cell infiltration, cell to cell adhesion, and replication, many of which have zinc as part of their MMP complex. It is possible that the zinc chelating properties of tetracyclines may also aid in inhibiting COVID-19 infection in humans limiting their ability to replicate within the host. Tetracyclines might be also able to inhibit RNA replication on positive-sense single stranded RNA, like COVID-19. For example, one study deduced a mechanism discerning how doxycycline could potentially treat the dengue virus. They also showed that at normal human body temperature and fever conditions, doxycycline significantly inhibited the virus’ own serine protease as well as noting a concentration dependent decrease in viral replication. They also found that doxycycline inhibited the post infection replication in addition to reducing the viruses’ ability to enter the cultured cells. Another study showed that retroviral load was decreased by 70% when cells were treated with the doxycycline at human body temperature We believe that tetracyclines can be potential therapeutic agents for COVID-19 that is hiding in plain sight. Moreover, tetracyclines overall are much safer agents than other potential agents that have been considered to treat COVID-19, such as chloroquine or antiretroviral drugs. We strongly urge international research groups to consider investigating the potential therapeutic efficacy of tetracycline antibiotics in treating COVID-19. To read more- https://accpjournals.onlinelibrary.wiley.com/doi/epdf/10.1002/phar.2395 Source- accpjournalsDr. Rama Chauhan9 Likes7 Answers
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Studies are beginning to show that, in rare cases, people with severe COVID-19 may develop the serious nervous system disorder known as Guillain-Barre syndrome. "Guillain-Barre syndrome is a well-known condition in which one's immune system targets peripheral nerves as foreign and attacks them, resulting in the cardinal features of the disease," explained Dr. Anthony Geraci, who directs neuromuscular medicine at Northwell Health in Great Neck, N.Y. The symptoms of the disorder "include weakness, areflexia [absence of reflexes], paresthesia [tingling], and in some cases facial weakness and ataxia [poor balance]," Geraci said. It's not uncommon for severe cases of infectious disease to trigger Guillain-Barre, experts noted. According to the Italian authors of a new study, the syndrome has also been seen in patients battling Epstein-Barr virus, cytomegalovirus and, most notably, infection with mosquito-borne Zika. The new study was authored by a team of doctors battling a major outbreak of COVID-19 in the northern Italian city of Pavia. Between Feb. 28 and March 21, three hospitals in the region treated about 1,200 patients with COVID-19. Five of those patients displayed symptoms most likely caused by Guillain-Barre, the team said. Symptoms of Guillain-Barre tended to arise within five to 10 days of the first onset of common COVID-19 symptoms, the researchers said. These first Guillain-Barre symptoms included weakness in the legs, tingling and facial weakness. Within another two days, neurologic symptoms got worse until all four limbs were weakened or paralyzed, the Italian group said. All five patients received immune globulin therapy to boost their immune response to the coronavirus, and one patient was treated with the antibody-rich blood plasma of a COVID-19 survivor. A month into treatment, "two patients remained in the intensive care unit [ICU] and were receiving mechanical ventilation, two were undergoing physical therapy because of flaccid paraplegia and had minimal upper-limb movement, and one had been discharged and was able to walk independently," according to the report. Dr. Sami Saba is a neurologist at Lenox Hill Hospital in New York City. Reading over the findings, he agreed that "many infections can be triggers for Guillain-Barre syndrome, so it is not entirely surprising that we are seeing cases associated with the novel coronavirus." "In those cases, weakness and sensory loss can be very difficult to identify if they are not awake, moving their limbs, or able to tell you what they are experiencing," Saba said. "However, since Guillain-Barre can affect the muscles that help us breathe, it will be very important to consider the diagnosis in those who have trouble coming off the ventilator, especially if their lung function looks to be recovering." For his part, Geraci stressed that Guillain-Barre remains quite rare -- just five cases out of 1,200 in this new study. He agreed that a variety of tests are needed before a firm diagnosis of the syndrome can be made. Source-https://www.drugs.com/news/some-covid-19-patients-stricken-guillain-barre-syndrome-89736.htmlDr. Kashish Garg9 Likes7 Answers
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"COVID - 19" ------------------ C➡️COUGH O➡️ORAL DISCOMFORTNESS V➡️VULNERABLE I ➡️ILLNESS SERIOUSLY D➡️DIFFICULTIES IN BREATHING Don't spread misguided news about "Corona virus" PROPHYLACTIC TREATMENT -------------------------------------------- Antitussive Antiallergic Antipyretic Praziquantel Antibiotics....prophylaxis Ribavirin Other manage accordingly..... Medical person should not be lily- livered. Should be strong....and fight against COVID-19 Lastly more important....awareness..... Corona virus comes from animals, Veterinary doctors can also play important role...... I just try post......Dr. Maqusud Ansari16 Likes24 Answers