Anorectal biopsy

38 yr, male multiple rectal and sigmoid ulcers. ?? Ulcerative colitis ?? Dysplasia?? What's your opinion..?!?

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Cryptitis Stromal inflammation Dysplastic glands. Focal crypt abscess No fissure ulcer No granuloma. Dd. Indeterminate colitis Early UC please correlate with colonoscopic findings

Looks IBD with mild to mod dysplasia ? Ulcerative colitis with malignant transformation

Amoebic colitis must be considered. Structures resembling amoebae with eosinophils are seen.

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