52 year old lady presented with phobia, visual hallucinations from 1 month, progressive cognitive decline, rigidity, abnormal posturing of limbs from 10 days, startle response to sound, myoclonic jerks, pseudobulbar affect, bladder and bowel incontinence from 1 week. No h/o fever.

1 Like


Progressive supranuclear palsy The cardinal manifestations of PSP are as follows: Supranuclear ophthalmoplegia Pseudobulbar palsy Prominent neck dystonia Parkinsonism Behavioral, cognitive, and gait disturbances that cause imbalance Frequent falls/impaired postural reflexes

Creutzfeldt–Jakob disease

More specifically variant CJD

its CJD


myoclonic jerks r very characteristic of sspe..may b subacute sclerosing panencephalitis

Clue is in characteristic MRI n EEG..

View 1 other reply