56yrs male known case of carcinoma buccal mucosa. has taken radiotherapy and chemotherapy. now presented with ulceroproliferative lesion at the same site. hpe images ?recurrence/? radiation induced changes

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Paucicellular areas with fibrosis along with atypical cells of Reactive/ Reparative nature.


Thank you all for valuable opinions Reported as radiation induced changes and reparative changes

Radiation induced changes

Radiation induced change.



Compare the slides of previous lesion with this one... This slide shows tumor cells with fibrosis...

Less cellularity, More fibrosis , atypical cells present ... can be residual tumour cells ...

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