59 year old female occasional bleeding during sexual intercourse.A tumor in the vagina was suspected. Dx?

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Gross : c/ s of uterus & Cervix. Polypoidal, lobulated massive solid grey white growth, appears to be arising from cervico vaginal region with areas of hemorrhages. Endometrium atrophic. Myometrium ? 3cm in width. No lesion in Endometrium / Myomeyrium. HPE : Malignant Spindle cell neoplasm arranged in intersecting bundles with nuclear pleomorphism & Good number of pleomorphic tumor giant cells & mitosis. Impression : Leiomyosarcoma. Advised IHC with SMA, H- Caldesmon.

MESENCHYMAL neoplasm..malignant. Dd. Leiomyosarcoma/GIST ...MALIGNANT MIXED MESODERMAL TUMOR. SUG.CLINICAL CORRELATION IHC

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Leiomyosarcoma advised IHC

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Leiomyoma / Leiomyosarcoma However, IHC for needful.

Leiomyosarcoma/ leiomyoma

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Leiomyosarcoma

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? Leiomyosarcoma

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Leiomyosarcoma.

Leiomyosarcoma

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Malignant spindle shaped tumor possibly leomyosarcoma

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