69 years male Pathological fracture hip joint Excision biopsy for comments

6 Likes

LikeAnswersShare

Metastatic Tumor Deposits With Clear Cell Morphology Leading To Pathological Fracture Possibly Metastasis From Clear Cell Renal Cell Carcinoma Adv - Imaging and Clinical Correlation

I have posted this case previously as well biopsy of the same patient on curofy but it was reported as osteosarcoma...by you and others as well... How is this possible... Even i have the same Opinions
0

View 6 other replies

This is Classic Metastatic deposits of Clear cell Renal Cell Carcinoma. I agree with Dr. Mohit Rajpal, one has to be wary/ cautious about Pseudosarcomatous Reactive proliferations at fracture site, the great mimickers of Osteosarcoma.

Mam I have seen last slides back now they are having osteogenic areas and I saw back these pictures also carefully which show nesting pattern of tumour cells and this also looks like Osteogenic ostesarcoma only

Here it seems to be clear cell carcinoma/ sarcoma Mets. Thus, Detail clinical history ,imaging and IHC needed for evaluation and diagnosis.

There is no obvious tumour osteoid noted. * Morphology consistent with Clear cell Renal cell carcinoma, Metastatic to bone. Advised IHC to differentiate between OS & RCC.

Metastatic deposits Probably clear cell ca or clear cell sarcoma

Sir I have posted this case previously as well biopsy of the same patient on curofy but it was reported as osteosarcoma... How is this possible...?
0

Reported as Metastatic tumor deposits with clear cell morphology possibly from clear cell RCC leading to pathological fracture and bone remodelling..

Clear cell carcinoma metastatic deposits Check for primary

Madam Please post previous pictures for review

Mets(adenocarcinoma)

Load more answers