Informative post sir
The genetic code of covid19 has similarities with HIV virus & malarial parasite & hence initial success with both retroviral & antimalarial drugs. Also testes may act as reservoir of infection .males are more affected as compared females & harmones maybe responsible for it. We are awaiting more data on this.
The possibility made out is not confirmed for every case. This will be safe as virus cannot replicate in Male reproductive system. Precaution to be taken 14 days after symptoms of COVID-19 have subsided
As the days progress we will come to know many new things about covid19. I will like to wait for 6 months and then make final list of important facts. Still we may come across new things.
It's informative and useful. Covid 19 throat swabs and nasal swabs. Antibodies test in serum . Covid 19 virus found in peritoneal fluid,
Being a Reproductive Endocrinologist, its the topic i am gathering researches and data base.. Thanx for providi g other angle.
If so then semen testing will be mandatory before marriage ?? . Now Covid 19 has given vast scope for Research & Publications
It is present in all the body fluids of a completely infected person (patient)
Informative post.... Needs more study... thanks for sharing.
All body fluid of infected person Contain SARS COV 2
Cases that would interest you
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THE COVID-19 SYMPTOMS WE DID NOT KNOW ABOUT As the pandemic spreads around the world, doctors are beginning to scope the coronavirus’s damage. Seen initially as a cause of viral pneumonia during the chaos of an explosion of cases in China, it’s now emerging as an enigmatic pathogen capable of harming the body in a myriad of unexpected, and sometimes lethal, ways. Clinical manifestations range from common cold-like symptoms and bronchitis to more severe disease such as pneumonia, severe acute respiratory distress syndrome, multi-organ failure and even death. The illness may occur as a direct result of viral infection, as well as the body’s response to it. Here’s a snapshot of some of the symptoms Covid-19 causes, including some you might not have heard about. Blood Fever and inflammation may disrupt blood vessels, rendering blood cells more prone to clumping while interfering with the body’s ability to dissolve clots. That may trigger a clotting cascade that can lead to blood-vessel blockages in tissues and organs throughout the body. Life-threatening clots in the arteries of the lung, known as pulmonary emboli, may occur even after symptoms of the infection have resolved. Damaged blood vessels may become leaky and prone to bleeding. In children, inflammation of veins and arteries triggered by excessive immune activation may cause an illness similar to Kawasaki disease, an inflammatory disorder. Brain Dysfunction in the lining of blood vessels and associated bleeding and clotting disorders may cause strokes and bleeding in the brain. Patients may also experience headache, dizziness, confusion, impaired consciousness, poor motor control, delirium and hallucinations. Eyes Red, puffy eyes, sometimes referred to as pink eye, may result from infection in the conjunctiva, the tissue that lines the inside of the eyelids and covers the white part of the eye. Gastrointestinal tract Infection of cells lining the digestive tract may cause diarrhea, nausea, vomiting and abdominal pain. Blood-vessel blockages caused by abnormal clotting have been found to damage the bowel, requiring emergency surgery and resection. Hands Prickling or burning sensation in the hands and limbs may indicate Guillain-Barré syndrome, a rare nervous-system disorder that may be triggered by aberrant immune responses to viral infection. Other symptoms of the syndrome include poor coordination, muscle weakness and temporary paralysis. Heart Cardiac injury, sometimes leading to irregular heartbeat, heart failure, and cardiac arrest, may occur as a result of excess strain, inflammation of the heart muscle and coronary artery, blood clots, and overwhelming multi-organ illness. Infection, fever, and inflammation in people with existing heart-vessel blockages may cause their fatty plaques to break off, blocking or stopping blood flow in organs and tissues. Limbs Obstructions in large blood vessels may cause insufficient flow, or acute ischemia, in the limbs. Severe vascular complications can be lethal. At least one reported cases resulted in lower limb amputation. Liver Liver dysfunction may occur as a direct result of the viral infection, or more likely because of immune-mediated, systemic inflammation and circulatory blockages cutting blood flow to the organ. Lungs The virus targets the epithelial cells that line and protect the respiratory tract as well as the walls of the tiny grape-like air sacs, or alveoli, through which gas exchange occurs to oxygenate the blood. Damage to alveoli and inflammation in the lungs can cause pneumonia, characterized by chest pain and shortness of breath. In severe cases, the lack of oxygen can trigger acute respiratory distress syndrome, leading to multi-organ-system failure. Kidneys Acute kidney injury may result from clots and impaired blood supply, or as a direct result of infection. Nose and tongue While the virus can cause the sneezing and runny nose typical of a common cold, it can also disrupt the olfactory system, causing an abrupt full or partial loss of the sense of smell known as anosmia. Taste may also become distorted in a condition known as dyguesia. Skin Hive-like rashes, small red dots and purplish discolorations on the legs and abdomen are part of a complex category of so-called paraviral dermatoses that may result from the body’s immune response to the virus or from benign, superficial blood-vessel damage beneath the skin. Toes Purple rashes that resemble chickenpox, measles or chilblains may appear on the feet, especially of children and younger adults.Dr. Prashant Ved16 Likes18 Answers
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A 60-year-old male presented with cough and dyspnea. He is a known Sarcoidosis patient. He is on cortisol treatment for 6 months. New Chest CT shows multiple mediastinal lymph nodes, interstitial sarcoidosis findings, and Pleural thickening. Newly presented Chest CT is almost same. Additionally bilateral ground-glass densities. The question: Is it alveolar Sarcoidosis or COVID 19?Dr. Ishan Ghorila8 Likes15 Answers
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Whether the patients with coronavirus disease 19 (COVID-19) infected by severe acute respiratory syndrome (SARS)-CoV-2 would commonly develop acute kidney injury (AKI) is an important issue worthy of clinical attention. This study aimed to explore the effects of SARS-CoV-2 infection on renal function through analyzing the clinical data of 116 hospitalized COVID-19-confirmed patients. Methods: One hundred sixteen COVID-19-confirmed patients enrolled in this study were hospitalized in the Department of Infectious Diseases, Renmin Hospital of Wuhan University from January 14 to February 13, 2020. The recorded information includes demographic data, medical history, contact history, potential comorbidities, symptoms, signs, laboratory test results, chest computer tomography scans, and treatment measures. SARS-CoV-2 RNA in 53 urine sediments of enrolled patients was detected by real-time reverse transcription-polymerase chain reaction. Results: Twelve (10.8%) patients showed mild increase of blood urea nitrogen or creatinine (<26 μmol/L within 48 h), and 8 (7.2%) patients showed trace or 1+ albuminuria in 111 COVID-19-confirmed patients without chronic kidney disease (CKD). All these patients did not meet the diagnostic criteria of AKI. In addition, 5 patients with CKD who were undergone regular continuous renal replacement therapy (CRRT) before admission were confirmed infection of SARS-CoV-2 and diagnosed as COVID-19. In addition to therapy for COVID-19, CRRT was also applied 3 times weekly during hospitalization for these 5 patients with CKD. In the course of treatment, the renal function indicators showed stable state in all 5 patients with CKD, without exacerbation of CKD, and pulmonary inflammation was gradually absorbed. All 5 patients with CKD were survived. Moreover, SARS-CoV-2 RNA in urine sediments was positive only in 3 patients from 48 cases without CKD, and 1 patient had a positive for SARS-CoV-2 open reading frame 1ab from 5 cases with CKD. Conclusion: AKI was uncommon in COVID-19. SARS-CoV-2 infection does not result in AKI, or aggravate CKD in the COVID-19 patients. To read more- https://www.karger.com/Article/FullText/507471 Source-American Journal of NephrologyDr. Vikrant Pachori10 Likes9 Answers
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People with asthma and other lung diseases are at increased risk for serious complications from COVID-19, caution experts from the American Lung Association. "Everyone's health is at risk from COVID-19, and those living with a lung disease or who are immunocompromised may be more vulnerable to the impacts of the virus," said Dr. Albert Rizzo, the association's chief medical officer. COVID-19 can cause a pneumonia-like lung infection, with a range of symptoms from mild or absent in some to life-threatening in others, he said. It's crucial for people with chronic lung diseases such as asthma or chronic obstructive pulmonary disease (COPD) to keep taking their maintenance medications and tell their health care provider about any symptoms or changes in their health, Rizzo said. All lung disease patients -- including those with lung cancer who may have a weakened immune system -- need to take steps avoid contact with the coronavirus. Besides social distancing, measures include thorough hand-washing; not touching face, nose, mouth and eyes; and avoiding contact with people who may have been infected. "The healthcare system and hospitals are already stressed with admissions as a result of the pandemic," Rizzo said. "It's important for those with lung disease to use their best practices in managing their disease." People who smoke or vape are also at increased risk of serious COVID-19 complications. "Cigarette smoking and vaping are linked to lung inflammation and lowered immune function in the lung's airways, both of which can increase likelihood of complications if exposed to COVID-19," he said. "Therefore, long-term smokers and e-cigarette users may have a higher risk of developing chronic lung conditions associated with severe cases." Source- https://www.drugs.com/news/asthma-copd-raise-odds-severe-covid-19-lung-experts-warn-89379.htmlDr. Vivek Jain6 Likes9 Answers
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A latest trial on CNS manifestations of COVID- 19. SOURCE- THE JOURNAL OF NEUROLOGICAL SCIENCES 413(2020) 116832. Journal home page : www.elsevier.com/locate/jns. Ali A.Asadi --Pooya Epilepsy research center, Shiraz university of medical sciences, Shiraz, IRAN Jefferson comprehensive Epilepsy center, Deptt.of Neurology Thomas Jefferson university of Philadelphia, USA . Leila Simani - Skull base research center, Loghman Hakim Hospital, Shahid Beheshti university of medical SCIENCES, Tehran , IRAN Corona virus is one of the major viruses that primarily targets the human respiratory system, but it also has neuroinvasive capabilities and can spread from the respiratory tract t to the CNS ..The most common symptoms of COVID- 19 , caused by SARS- COV- 2 are fever, cough and fatigue. Other symptoms are headache hemolysis, dypnoea and sometimes diarrhea. Patient may develop Pneumonia, ARDS, Acute cardiac problems and multi organ failure. COVID- 19 pandemic have been associated with neurological manifestations (e.g.febrile seizures, convulsions, change in mental status and encephalitis. Neurotropic and neuroinvasive capabilities of COVID- 19 have been described in humans. Upon nasal infection, corona virus enters the CNS through the olfactory bulb, causing inflammation and demyelination.. While neurological manifestations of COVID- 19 have not been studied appropriately , yet it is highly likely that some of these patients, particularly those who suffer from severe illness, have CNS involvement and neurological manifestations 1. Precise and targeted documentation of the neurological symptoms (headache , dizziness etc) and signs ( change in mental status, meningeal signs etc) , 2.Detailed clinical, neurological and electrophysiological investigations ( e.g EEG) of the patient particularly those with a change in mental status, 3.Attempts to isolate SARS- COV- 2from CSF and autopsies of COVID- 19 victims , May clarify the roles played by the virus in causing neurological manifestationsDr. Parveen Yograj3 Likes5 Answers