What is the difference between hot and cold thyroid nodule in terms of malignancy association

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Feeling too hot or cold - Thyroid disorders can disrupt the ability to regulate body temperature. People with hypothyroidism may feel cold more often than usual. Hyperthyroidism tends to have the opposite effect, causing excessive sweating and an aversion to hear. The thyroid, an endocrine gland just above the collarbone, produces hormones to regulate functions such as heartbeat and metabolism. The gland also controls your body temperature. When the body makes too much thyroid hormone, body temperature rises. Nodules that produce excess thyroid hormone — called hot nodules — show up on the scan because they take up more of the isotope than normal thyroid tissue does. Hot nodules are almost always noncancerous. In some cases, nodules that take up less of the isotope — called cold nodules — are cancerous For last para i agree with my daughter..Dr.Thirumala.Sepuri.
Thank you Papa, Pranams Papa
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Hot thyroid nodules produce more Thyroid hormone and take more radioisotope and show up on the scan . These hot nodules are almost always non cancerous . Cold Thyroid nodules produce less thyroxine and donot take up radioisotope . 5% of cold nodules are cancerous . 95% of thyroid nodules are cold nodules .USG Thyroid followed by FNAC decides whether the Thyroid nodule is benign or malignant.
Nodules that produce excess thyroid hormone- called hot nodules- show up on the scan because they take up more of the isotope than normal thyroid tissue does. Hot nodules are almost always noncancerous. In some cases,nodules that take up less of the isotope- called cold nodules-are cancerous
Hyperactive nodule as graves disease presents as hyperthyroidism Surgically can be removed and treated as hypothyroidism Cold nodule is like goitre nodule inactive and euthyroid Surgically can be treated
Thanx dr Vipin Bihari Jain
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Both can be malignancy. But the incidence of malignancy is more common in cold nodules. If an isolated cold nodule seen in thyroid the chances of malignancy is more. For such cases a USG guided FNAC to be done before further treatment.

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