A 55 yr old female Image guided fna from liver nodules. Patient had multiple nodules.

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Cytosmears prepared are cellular showing numerous scattered and ill formed clusters of monomorphic population of small round cells with round to oval to eccentric nucleus, clumped nuclear chromatin , occasional conspicuous nucleoli and moderate cytoplasm . Impression - Guided FNAC multiple liver nodules -Metastatic small round cell tumor Possibilities 1. Metastatic Non Hodgkins Lymphoma 2. Metastatic Neuroendocrine Tumor ( GIT) 3 Metastatic Medullary Carcinoma Thyroid 4 Primary Hepatic Lymphoma ( Rare) To correlate with Clinical and Radiological Findings

Good description Dr Mohit
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High yield cytosmears revealed cells in loose clusters & discohesive individually scattered cells with high NC ratio,mild nuclear pleomorphism.P/O *Primary/Metastatic Lymphoma. Metastatic SRCT.Multicentric PD/HCC. Advised Bx & IHC.

HCC Multicentric

Metastatic tumor deposit

Cellular smears,isolated cells loosely cohesive clusters,round nuclei,inconspicous nucleoli, central to eccentric uclei ocasional acinar formation.possibilites suggested are_ metastatic adenocarcinoma.2) metastatic neuroendocrine carcinom.

Small round cell carcinoma

Metastatic carcinoma. Possibility of primary being 1. Thyroid, 2. Neurologist endocrine tumour from GIT.

Findings suggest metastatic carcinoma.? Primary pancreas. CA19.9 level?

Metastatic adenocarcinoma

Neuroendocrine

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