A chronic smoker with Progressive Dyspnea

Patient came for medical checkup required for his new job. There is no chief complaint as such. What is the abnormality here and how to proceed?

Age 52/m diabetic have this color change, history of dvt and copd and was taking warferin.. Started with minocycline recently... What could be the reason for Color change?? And how can we manage it?

A 72 y/o male with a history of COPD and recent pneumonia was treated with oral prednisone 40 mg daily, antibiotics, and a fluticasone-salmeterol inhaler. One week during treatment, the patient developed painful oral lesions. examination revealed many white-tan plaques on the lower lips, tongue, and posterior aspect of the oropharynx. Lesions do not respond to nystatin oral suspension. What is diagnosis and management for the case?

A 72 year old farmer is seen for a check up prior to inguinal hernia repair. A chest xray is requested as he has a smoking history. An interesting incidental discovery is made. Note that the image contrast has been manipulated to best show the abnormality.

75 yr/F. Lump Lt Breast. no other local or systemic complains. known COPD since long. Dx and Mx