A middle aged male with Secondaries in Spleen

A male aged 50 years Chief Complaints Loss of Weight Pain LUQ Anorexia since 1 month Physical Examination Nothing significant Investigations Found to have Secondaries in spleen with Unknown Primary Diagnosis What shd be the dd for him and approach to treatment

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How have come to know that it is secondaries spleen Can you justify

What investigation has suggested secondaries Spleen kindly justify