A patient presented to the Department of Pathology with chief complaints of Shortness of breath, Fever and body aches. Her blood profile: HB : 12 gm%, Platelets : 53,000/cumm, DLC : N: 25, L: 73, M: 02 ( on Cell counter) Peripheral blood smear examined. Probable diagnosis and further course of management?

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-Atypical lymphocytes Lymphocytic leucocytosis with thrombocytopenia However,detail clinical evaluation (+ organomegaly), PBS, flow cytometry to be carried out for needful.

Lymphocytic Leukocytosis with atypical lymphoid cells with Thrombocytopenia. In the scenario of normal Hb% & TWBC count, first possibility would be to R/O Viral aetiology. However advised Flow cytometry/ Immunophenotyping.

Lymphocytic leucocytosis Atypical lymphocytes present Do flow cytometry to exclude any abnormality because of thrombocytopenia

Virocytes Work up for Dengue /Chikunguniya Hepatitis Typhoid etc by serology.

Transformed (atypical) lymphocytes. Also called. DOWNEY CELLS. VIROCYTES. SUG.CLINICAL CORRELATION. ....MONOSPOT

First rule out viral etiology Take history and do other Investigations What about total WBC count

Tlc is 11300..
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Plasmodium vivax. Malaria

Reactive lymphocytes. Lymhocytosis. Dengue fever to rule out

Atypical lymphocytes, exclude Infectious mononucleosis

PCP. Organism .. Pneumonitis.. exclude HIV

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