peraquat poisoning
A pt has come to us with peraquat poisoning with msof (Kidney failure raised liver enzymes and respiratory distress ) after 10 days she had decrease spo2 x ray given below hrct also done showd ild like picture
Paraquat poisoning Paraquat (dipyridylium) is a highly toxic weed killer (herbicide). In the past, the United States encouraged Mexico to use it to destroy marijuana plants. Later, research showed this herbicide was dangerous to workers who applied it to the plants. This article discusses the health problems that can occur from swallowing or breathing in paraquat. This article is for information only. DO NOT use it to treat or manage an actual poison exposure. If you or someone you are with has an exposure, call your local emergency number (such as 911), or your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. Causes In the United States, paraquat is classified as "restricted commercial use." People must obtain a license to use the product. Breathing in paraquat may cause lung damage and can lead to a disease called paraquat lung. paraquat causes damage to the body when it touches the lining of the mouth, stomach, or intestines. You can get sick if paraquat touches a cut on your skin. Paraquat may also damage the kidneys, liver, and esophagus (the tube that food goes down from your mouth to your stomach). If paraquat is swallowed, death can quickly occur. Death may occur from a hole in the esophagus, or from severe inflammation of the area that surrounds the major blood vessels and airways in the middle of the chest. Long-term exposure to paraquat may cause scarring of the lungs called pulmonary fibrosis. This makes it hard to breathe.
CXR..STUDY.. GGO.. ? ILD .. NEED'S.. HRCT STUDY.. RT..PCR..COVID-19..
supportive medication for kindey failure Rx Punarnavashtak qwath BD Galo ghan tab 1BD Making of kadha (Punarnavashtak qwath) : ek glass pani me 2 Chamach punarnavashtak kadha(bhuka) dalke ubalna he, 1/3 baki rahe tab usko chhanke lukewarm pina he.)
रोगी का पूरा व्योरा भेजे जिसमें निदान हेतु विचार किया जा सके।
Pulmonary fibrosis with organ failure. Activated charcoal, complete plasma transfusion, critical care unit referral.
Pomegranate juice beetroot lime juice coriander juice... foods low in potassium magnesium. Lemongrass decoction with haldi...no sugar no nonveg diet no eggs no mushrooms no fried foods no processed or fermented foods and beverages..no vyasan..no stress....under strict supervision of Doctor
Refer to a specialist doctor
Rx tiryaq arwa Arq mako Arq kasni Majun dabeedul ward
Ars.alb.200/3dose Carbo.veg 30/tds for 7days
Rx Similimum
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Chronic kidney failure, also known as chronic renal failure, chronic renal disease, or chronic kidney disease, is a slow progressive loss of kidney function over a period of several years. The symptoms of worsening kidney function are non-specific, and might include feeling generally unwell and experiencing a reduced appetite. CKD is initially without specific symptoms and is generally only detected as an increase in serum creatinine or protein in the urine. Later on there is- increased urination, especially at night decreased urination blood in the urine (not a common symptom of chronic renal failure) urine that is cloudy or tea-coloured puffy eyes, hands, and feet (called edema) high blood pressure fatigue shortness of breath loss of appetite nausea and vomiting (this is a common symptom) thirst bad taste in the mouth or bad breath weight loss generalized, persistent itchy skin muscle twitching or cramping a yellowish-brown tint to the skin Pathology- A normal kidney contains approximately 1 million nephrons, each of which contributes to the total glomerular filtration rate (GFR). In the face of renal injury (regardless of the etiology), the kidney has an innate ability to maintain GFR, despite progressive destruction of nephrons, as the remaining healthy nephrons manifest hyperfiltration and compensatory hypertrophy. This nephron adaptability allows for continued normal clearance of plasma solutes. The hyperfiltration and hypertrophy of residual nephrons, although beneficial for the reasons noted, has been hypothesized to represent a major cause of progressive renal dysfunction. Causes- Type 1 or type 2 diabetes High blood pressure Glomerulonephritis Interstitial nephritis, an inflammation of the kidney’s tubules and surrounding structures Polycystic kidney disease Prolonged obstruction of the urinary tract, from conditions such as enlarged prostate, kidney stones and some cancers Recurrent kidney infection, also called pyelonephritis Types- Each patient is classified into one of the following 5 stages of CKD according to the progression of damage. Stage 1: Kidney damage with normal or increased GFR(>90 mL/min/1.73 m2) Stage 2: Mild reductionin GFR (60-89 mL/min/1.73 m2) Stage 3: Moderate reductionin GFR (30-59 mL/min/1.73 m2) Stage 4: Severe reductionin GFR (15-29 mL/min/1.73 m2) Stage 5: Kidney failure(GFR <15 mL/min/1.73 m2 or dialysis) Complications- Anemia – hemoglobin levels drop and not enough oxygen reaches many parts of the body. Central nervous system damage. Dry skin, skin color changes. Fluid retention – this can lead to swollen tissue, heart failure, and fluid build-up in the lungs. Hyperkalemia– blood potassium levels rise; this can result in heart damage. Insomnia – this is a common consequence of kidney failure Lower libido (sex drive) Male erectile dysfunction. Osteomalacia– bones become weak and break easily. Pericarditis – the sac-like membrane that envelops the heart (pericardium) becomes inflamed. Stomach ulcers. Weak immune system– the patient becomes much more susceptible to infection. Complications in children: Erythropoietinproduction drops, resulting in a much lower red blood cell count. Vitamin D – the kidneys will no longer be able to activate vitamin D, resulting in poor calcium absorption and muscle function. Consequently, children with kidney failure may fail to grow properly. Complications during pregnancy: When a woman is pregnant the kidneys have to work especially hard because the amount of fluid in the body increases. Pregnant women with chronic kidney failure may experience worsening hypertension and an increase in waste products in their blood. This can affect both the mother and her baby. Women with chronic kidney failure who are pregnant have a significantly higher risk of developing preeclampsia, compared to other women – blood pressure rises dangerously high. If left untreated the result could be a brain hemorrhage, or hemorrhaging in the liver or kidneys – both potentially fatal for both mother and baby.
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