Concluded Case

Baby born of VDRL POSITIVE mother

A VDRL positive mother delivered a baby which is also VDRL POSITIVE ( done after 3 days of birth). Mother had already received injection penidure LA 12 . Baby is other Healthy. Should baby be given injection Benzathine penicillin G 50,000 unit /kg i.m ?

(Edited)

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Concluded answer

Final diagnosis should not be made on the basis of result of a single test, but should be made on co-relation of test results with other clinical findings. confirmatory FTA-ABS test should be performed if VDRL or RPR is positive Treatment decisions frequently must be made on the basis of (1) identification of syphilis in the mother; (2) adequacy of maternal treatment; (3) presence of clinical, laboratory, or radiographic evidence of syphilis in the infant; and (4) comparison of maternal (at delivery) and infant nontreponemal serologic titers using the same test and preferably the same laboratory. Venous blood from both the mother and the child should be tested. Asymptomatic congenital syphilis requires a comprehensive approach. All infants born to mothers who have reactive nontreponemal and treponemal test results should be evaluated with a quantitative nontreponemal serologic test (RPR or VDRL) performed on infant serum because umbilical cord blood can become contaminated with maternal blood and could yield a false-positive result and should be examined thoroughly for evidence of congenital syphilis (e.g., nonimmune hydrops, jaundice, hepatosplenomegaly, rhinitis, skin rash, and/or pseudo paralysis of an extremity). Conducting a treponemal test (i.e., TP-PA or FTA-ABS) on a newborn's serum is not necessary.

All Answers

Final diagnosis should not be made on the basis of result of a single test, but should be made on co-relation of test results with other clinical findings. confirmatory FTA-ABS test should be performed if VDRL or RPR is positive Treatment decisions frequently must be made on the basis of (1) identification of syphilis in the mother; (2) adequacy of maternal treatment; (3) presence of clinical, laboratory, or radiographic evidence of syphilis in the infant; and (4) comparison of maternal (at delivery) and infant nontreponemal serologic titers using the same test and preferably the same laboratory. Venous blood from both the mother and the child should be tested. Asymptomatic congenital syphilis requires a comprehensive approach. All infants born to mothers who have reactive nontreponemal and treponemal test results should be evaluated with a quantitative nontreponemal serologic test (RPR or VDRL) performed on infant serum because umbilical cord blood can become contaminated with maternal blood and could yield a false-positive result and should be examined thoroughly for evidence of congenital syphilis (e.g., nonimmune hydrops, jaundice, hepatosplenomegaly, rhinitis, skin rash, and/or pseudo paralysis of an extremity). Conducting a treponemal test (i.e., TP-PA or FTA-ABS) on a newborn's serum is not necessary.

Only on basis of once VDRL test positive in new born anti syphilitic tt shud be not started immediately. There may be other signs eg. Rashes & sores etc.Better to consult Paediatrician for needful or VDRL test of baby shud be repeated after a wk of birth before taking any decision.

Yes Should be given

Diseases Related to Discussion

Congenital Syphilis
Syphilis
Rhinitis
Rashes