Concluded Case

APL

16 years female with cbc and peripheral blood smear for interpretation

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Concluded answer

N/N. Thrombocytopenia. Leukocytosis.Increased blasts > 20% with auer rods.Acute Leukemia/AML P/O : APML/ AML - M4.Advised Spl.Stains,BMA & FCM.

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Flow cytometry Positive: cd45, 64 , 13, 33, MPO and partial cd4 positive Negative: 10, 34, 117, 15, 14, 11c, HLA DR, 61, 5, 7, 2, 3, 19, 20, 22. APML Further genetic study needed

AMML.. AML M4.. Auer rods. Sug. Bone marrow study Special stains Immunophenotyping Flow cytometry Cytogenetic study

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RBCS normochromic normocytic Platelets reduced Leucocytosis Blasts promyelocytes with Auer rods Acute leukemia Possibly APML M4 Adv BM and FCM

N/N. Thrombocytopenia. Leukocytosis.Increased blasts > 20% with auer rods.Acute Leukemia/AML P/O : APML/ AML - M4.Advised Spl.Stains,BMA & FCM.

Thank you doctor
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SUGGESTIVE OF A M M L A. M. L.... M 4. M5 NEEDS. FURTHER. EVALUATION

Acute hypergranular promyelocytic leukemia Phagot cells +

Faggot cells
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Looks Acute Leukemia AML M4 Adv: BMA and FCM

Why not APML sir
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Blasts with granulesand auer rods. APML

Nice.picAML

Increase wbc with thrombocytopenia with anemia Acute lymphocytic leukemia

Acute leukemia then further after Flow cytometry we can decide the type
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