a 65 yr old Male, complaining pain in left knee, what can be the possibilities???

middle aged male, with 3 months history of progressive, unilateral 2,3,4 pip joint swelling, no significant pain n tenderness . no complaints in other joints,no low bachache no skin lesions. no significant past history or comorbidity.. RA n CCP neg. HLAB27 neg. CRP n ESR postv. kindly opine fr d DX.

pt. 46yr. c/o pain in left knee from 2-3 days. no h/o trauma .No bp. and DM. please diagnosis and Rx.

A 38yrs/f suffering from joints pain(big) with puffy face and pedal oedema since 2 months. Pt is obese and hypertensive(on telmisartan+amlodipine) since last 10 yrs. Increased frequency of micturition with lower abd pain since 6 month. Non diabetic. Usg w/a reveals thickening of uterine endometrium and gr | fatty liver. Urine exam- WNL. Plz suggest treatment acordingly.

54 years male patient complains of pain and swelling in the right lower thumb. since 6 months he is a diabetic patient hba1c is 8.3 cbc is normal uric acid is increased a bit no other systemic disease he is a driver by occupation doppler reports are attached. he is a chronic smoker. there is change in colour at the thumb region compared to the normal side what cud be the provisional diagnosis