BPH

He is known case of T2DM + HTN with Past history of Stroke too Management Best drug to add him on silodosin or tamsulosin along with Dutasteride? Confused between Tamsulosin or Silodosin

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To select between two depends on how much retention and bladder combating with back pressure Since pt is hypertensive and diabetic must be on rx considering the control and molecule you may select any one Since both are Alpha blockers silodosyn is selective one I don't think this will have any postural hypotension in comparison to tamsulosan. If pt is on ACE OR ARB it is not going to be measure hurdle but if pt is on betablockers than it becomes alpha beta blocker and pt may experience dizziness

Thanx dr Kute Ankush
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Advantages of Silodosin - quicker onset of action , and no postural hypotension.. Disadvantage is sexual dysfunction like retrograde ejaculation . Advantage of tamsulosin is in asexually active males. But it can produce postural hypotension ,which is a disadvantage. In this case since patient has many comorbidities, and older age group , silodocin may be a better choice Both drugs have the same efficacy.

SILODOSIN .. AS IT IS MOST EFFICACIOUS AB .. WITH RAPID ONSET OF ACTION .. ALSO IMPROVES QUALITY OF LIFE .. IN .. PATIENTS WITH.. LUTS .. DUE TO BPH ..

Tnx &wc Dr Ajeet Singh
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To add tab Tamsulosin and Dutasteride not tab silodosin because it cause sudden drop of blood pressure and causes dizziness.

Thanks Dr Ajit Singh.
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