CONG ANAMOLIES ASSOCIATED WITH OPTIC DISC

4 yr M chiild c/c diminished vision since 2 yrs .O/E bilateral iris coloboma , left eye , left cornea small , vision more decreased in left eye than Rt eye.Pt was referred to Opthalmologist thrice.Paretents were told that no treatment is available. Anti natal h/o- normal .Full term normal delivery. Family h/o -normal .Growth &development normal except eye & vision problem. Diagnosis &Rx ?Recent Advances in treatment. Role of stem cell therapy.

15 days Infant with lesions since birth. dx & Rx ?

Good evening revered Curofians. Posted below is a interesting eye pictograph. Kindly give your valuable opinions. Best regards. (Credit : Internet)

congenital absent of closure of lid/lagophthalmos in a mch age 2days .please suggest what can be done for this child.

A coloboma describes conditions where normal tissue in or around the eye is missing from birth. Coloboma comes from the Greek word that means “curtailed.” The eye develops quickly during a fetus’ first three months of growth. A gap, known as the choroidal fissure, appears at the bottom of the stalks that eventually form the eye. This fissure generally closes by the seventh week of gestation. If it does not close, a coloboma or space forms. A coloboma can affect one or both eyes. If both eyes are involved, it can affect them the same way or differently. There are different types of coloboma, depending on the part of the eye affected: Eyelid coloboma- A piece of the upper or lower eyelid is missing. Lens coloboma- A piece of the lens, the part of the eye that focuses light onto the retina, is missing. Macular coloboma- The macula is the central part of the retina responsible for daylight, fine and color vision. In this coloboma, the macula fails to develop normally. Optic nerve coloboma- In this coloboma, the optic nerve, the bundle of fibers that relay light signals to the brain, is hollowed out, reducing vision. Uveal coloboma- The uvea is the middle layer of the eye. This coloboma can affect the iris, the colored part of the eye, giving it a distinct keyhole or cat-eye appearance. Chorio-retinal coloboma- In this coloboma, part of the retina (the light-sensitive tissue lining the back of the eye) is missing.