Can there be any chemical reaction,irritation severe effect if sodium bicarbonate mixed with lignox

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Baking soda, or sodium bicarbonate (NaHCO3), is a chemical that can undergo a decomposition reaction when heated. At temperatures above 176 degrees Fahrenheit (80 degrees Celsius), sodium bicarbonate starts to break down into three compounds, forming sodium carbonate (Na2CO3), water (H2O) and carbon dioxide (CO2)

WELCOME @ DR. SOUMYA. HAZRA. JI... SODIUM. BICARBONATE.....IS USED. TO... ....NEUTRALIZE. THE.... pH ...OF LIGNOX. OR LIGNOX +. EPINEPHRINE.. THE. ONLY. CONDITION. IS..... ... ..PROPER. RATIO. OF. MIXING. OF. SODIUM. BICARBONATE. AND. LIGNOX...

POSSIBLY.. URTICARIAL RASHES OR HIVES /. SKIN. RASHES

Yes..efficacy will not persist..opposing acton