Can we give Roxithromycin and Metformin together?

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Yes One case is known to me of Clarithromycine with anti diabetic drug caused hypoglycemic circus. Gatifoxicilline has also caused hypo and hyper glycemic crisis with antidiabetic medicines.

Yes.. Study shows Among macrolides Clarithromycin has interactions which causes hypoglycemia when combined with anti diabetic drugs... Azithromycin and roxithromycin are safe...still it's better to monitor for hypoglycemia while giving macrolides