Verrucous lesions since childhood in a male 17 years old . Diagnostic dilemma

identify this extremely rare autosomal recessive hereditary skin disorder.

Good morning dear friends and colleagues, Today let's have a look at TREE MAN DISEASE. It is also known as Epidermodysplasia verruciformis is an autoimmune deficiency. It is failed response to Human papilloma virus type2 and believed to stem from genetic defect. It is a rare genetic and inherited disorder and creates wart like lesions any where on the body. It is caused by HPV virus and characterised by wide spread skin eruptions, wart like lesions and reddish brown pigmented plaques. It is seen between 1 to 20 years of life and some cases reported in middleaged people. No definite cure except surgery. With regards, Dr Sepuri Tirumala Devi.

A 65 year house wife having lesions in skin over idex finger since 1 year ,not responding to Keratolytics ,conventional treatment.No pain or negligible pain.Sensation intact.No Hypertension,no diabetes,no lepromatous lesion.3 months back underwent laser debridement.Now recurred at same site.New lesion now also seen in other hand finger.

Multiple tiny warty lesions on forehead Since long duration .. No itching No burning... Histopathological image of this patient. What is probable diagnosis? Plane warts Epidermodysplasa verruciformis Acantholytic dyskeratotic acanthoma Epidermolytic hyperkeratotic acanthoma of HPV origin Basal cell papilloma Darier's disease