FLUVOXAMINE- A common OCD drug - in early treatment of COVID-19
Common OCD Drug May Be Used In Early Treatment For Covid-19: Scientists Fluvoxamine, typically used to treat patients with OCD, has strong anti-inflammatory properties. Scientists have found that a drug commonly used to treat obsessive-compulsive disorder, or OCD if taken within seven days of first symptoms of Covid-19, may reduce the risk for respiratory deterioration, an advance that might lead to a new treatment strategy for the novel coronavirus infection. The study, published in the journal JAMA, noted that none of the 80 patients who took the antidepressant fluvoxamine met the respiratory deterioration criteria -- compared to an 8.3 per cent rate in the 72 patients who took a dummy pill (placebo). "The results of the fluvoxamine trial are encouraging and warrant a further evaluation in a larger study. A treatment that can prevent lung problems in people with mild symptoms of Covid-19 is desperately needed," said study co-author Carolyn Machamer from the Johns Hopkins School of Medicine in the US. According to scientists, fluvoxamine, which is typically used to treat patients with OCD, has strong anti-inflammatory properties. They believe this capability could prevent cytokine storms -- the body's massive, sometimes deadly, inflammatory reaction to the coronavirus. In the study, the 152 trial participants, all of whom were 18 years or older, were diagnosed with mild forms of Covid-19, and randomly assigned to take either fluvoxamine or a placebo. The scientists said none of the 80 participants who received the drug hit the endpoint of clinical deterioration, as opposed to six of the 72 people in the placebo group whose blood oxygen levels significantly lowered. Based on the results, the researchers said fluvoxamine has the potential to reduce the risk of hospitalisation in Covid-19 patients. "We now have evidence that an inexpensive, safe, and readily available pill can reduce deterioration and hospitalisation from Covid-19," said Steve Kirsch, another co-author of the study
Encouraging study Sir it is well established fact the mental frustration and depression in a covid pt under goes hence addition of antidepressants is part of treatment So far study encompasses young generation with mild to moderate stage of covid infection The generation under review has good immunity in comparison to old pts where the disease playing its dragon effect Recovery in young generation is with in 7 days exceptions are there Hence addition of one more pill well its discretion
Impressive and informative post. Thanks for sharing.
Nice study to learn
Very informative. Thanks for sharing @Dr. Parveen Yograj sir.
Informative Post sir
उत्तम
USEFUL AND INFORMATIVE UPDATE
Nice information sir
Cases that would interest you
- Login to View the image
A female aged 45 years who is a k/c/o Hypothyroidism on treatment with Morbid obesity p/w complaints of Burning in Chest since last night....She also complains of Pain in Right arm....comment on her ECG and discuss the findings
Dr. Hardik Ahuja1 Like17 Answers - Login to View the image
A female 35 yrs old was admitted with complaints of pain Right Iliac Fossa since 7 days in some private nursing home was given treatment for the same but after treatment sge developed severe hemorrhagic lesions , bleeding from nose and mucosal surfaces and eruptions throughout the body....No documentation of the treatment she received could be retrieved....She developed Severe Pancytopenia....Discuss the cause and approach to this patient....
Dr. Hardik Ahuja7 Likes17 Answers - Login to View the image
A ninety years old female presented with painful lesions over her upper back,chest and overlying shoulder region for last 2 days. The lesions were accompanied with fever, agitation and restriction of movement of shoulder joint. Possible differentials and management? #learningwithvisuals
Shritik Devkota4 Likes16 Answers - Login to View the image
55 yrs old patients presented with central chest pain radiation to the limbs Bp=120/75 Puls 62 Whats ur diagnosis ??
Dr. Emad Hasan3 Likes28 Answers - Login to View the image
A male patient 55yr was admitted in our CCU with severe chest pain radiating to neck and Lt arm, palpitations, sweating, nausea, vomiting and Respiratory distress. H/o HTN, irregular drug intake. Trop-T was positive. ECG attached. Please give your valuable opinion.
Dr. Syamal Chattopadhyay1 Like19 Answers
2 Likes