D/Dx of Normal Total protein but low Albumin:Globulin ratio

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A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome).

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Total protein 6 to8 point3 g/dl Albumin 3 to5 point4 g/dl Globulin 2 to 3point5 g/dl Low albumin globulin ratio in Autoimmune disease Nephrotic syndrome Cirrhosis of liver Any chronic non healing ulcer with swelling clinically

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Low ag ratio reveals High production of globulin Such as Multiple Myeloma , autoimune disorders Low production of Albumin Such as chronic liver diease , cirrhosis , Increase loss of albumin Diabetic nephrology, nephrotic/nephrotic Syndrome

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Possible.. Any cause of Hypoalbuminaemia Or Hyperglobulinaemia. Myeloma Nephrotic syndrome Paraproteinaemias Cirrhosis Kalaazar Chronic infection

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Yes A/G ratio reverses in chr liver disease like cirrhosis Ckd Multiple myeloma ASH NASH

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