2 months old child with Hb 8.0 gm TLC 26000 plt 50000 Plz comment on PS findings.

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Rbc series : microcytic hypochromic Wbc seriers : leucocytosis mainly lymphocytisis with monocytes and atypical lymphocytes. Pleatlet : thrombocytopenia over all impression : LYMPHOCYTIC LEUCMOID REACTION also think for EVANS SYNDROME point favouring 1) child age 2) two series rbc and platelet decreases 3) leucocytosis mainly lymphocytosis and monocytosis further confirm by bonemarrow study , retic count , Ldh , imunoglobulin study.it is present as AIHA ( auto imune haemolytic anemia ) but rull out leukemia by flow cytometry too.
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Lymphocytic leukaemoid reaction dd. Atypical lymphocytosis Blasts. Leucoerythroblastic blood picture. modearte aniso poikilocytosis hypochromia..microcytosis. nrbc. plts low. sug. clinical correlation. bma..study. flowcytometry spl stains cytogenetic study. repeat cbc after a course of antibiotics
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Wbc count in 1-3 months -5000-19500 Here it is leucocytosis with atypical lymphocytes Advised flow cytometry of blood to exclude leukemia
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D/D 1.Lymphocytic Leukaemoid Reaction 2.ALL However,clinical evaluation,BM Study, flow cytometry and Cytogenetics for needful.
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Blast present Adv flow cytometry Keep patient on follow up to rule out transient leukemia of newborn
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LER, LR( Lymphocytic), P/O Acute Leukemia - ALL has to be ruled out. Advised : BMA, FCM.
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DD- -Lymphoid leukemoid reaction. -ALL. ADV- Special stain, BM and FCM
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lymphocytic leukemoid reaction. BM. study sugg. to rule out leukemia.
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Acute leukemia. Advised - bm exam, cytochemistry and flow cytometry.
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suggestive of congenital leukaemia
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