Diabetes management oha/insulin management
ORAL HYPOGLYCEMIA AGENTS :- A) BIGUANIDE Drugs - Metformin S/e :- Vb12 deficiency lactic acidosis Weight loss . 2) SULFONYLUREAS Glipizide Glimepiride S/e:- Alcohol reaction Weight gain 3)MEGLITINDE Rapeglinide Nateglinide S/e:- Wt.gain Hypoglycemia 4) THAILIDOMIDES Pioglitazone Rioglitazone S/e:- Hypoglycemia wt gain heart failure kidney failure 5)DDP4 INH Sitagliptin aglogliptin S/e:- Pancreatitis 6)SGLT2 INH Dapaglifozin Canaglifozin S/e:- Wt.loss UTI 7)Alpha-Glucornidase INH Acarbose Voglibose miglitol
Depends on HbA1c level,KFT and pt profile
Cases that would interest you
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30 year old male, 10 day history of diarrhoea and reduced oral intake, presented with lethargy and ongoing abdominal cramps. No respiratory symptoms, but O2 sats noted to be on the lower side, exertional O2 sats dropped to 86%. No past medical history of note, normal white cell count, not lymphopenic, urea 18.9 mmol/L, creatinine: 489 µmol/L, amylase 600 (30-118), ALT: 65, CRP: 100, Trop I 267 (0-46). Chest X-ray as shown. What do you think the patient is suffered from?
Dr. Somi Suyal2 Likes18 Answers - Login to View the image
pt of RHD not on warfarin ...presented with abdominal pain with brownish discoloration over abdominal wall ..since 6 days with abdominal tenderness ...jvp was raise and b/L pedal oedema ..on routine INR was 1.7, platelets 50000,wbc -14700, bilirubin 6 ,with sgot and sgpt was 100 and 300 ,kindly comment ....
Dr. Sumit Kumar Vishwakarma12 Likes24 Answers - Login to View the image
43 yo male came to the ER with severe SOB and coughing. Toxic and mildly feverish lethargic. Decreased air entry spo2 80.% crepits with wheezes. This is his CXR ! Opinions, please.
Dr. Ishan Ghorila3 Likes20 Answers - Login to View the image
78 y/o female complaints of severe right upper quadrant pain that radiated to the epigastric region and back associated with nausea and nonbilious vomiting. PMH: chronic pancreatitis, congestive heart failure, and poorly controlled type 2 diabetes. She underwent a remote cholecystectomy. Temp: 39.3°C, BP: 159/73 mm Hg, She appeared to be in severe distress. The epigastric and right upper quadrant regions were very tender to palpation. -Elevated serum glucose (369 mg/dL), low serum sodium (131 mmol/L), chloride (94 mmol/L), and bicarbonate (19 mmol/L). -Urine sample showed ketones, while serum BHB was elevated (1.64 mmol/L). -CT of the abdomen revealed duodenal thickening. Diagnosis of diabetic ketoacidosis was made and started appropriate treatment. She continued to vomit despite the use of anti-emetics, bowel rest, and diabetic ketoacidosis treatment. Upper endoscopy showed a distally black esophagus. What is it? How to proceed with treatment?
Dr. Sudhir Mann5 Likes18 Answers - Login to View the image
A 60 yr old female k/c/o T2DM, CAD (Post PTCA) Hypothyroidism presented with complaints of sudden onset breathlessness since 3 hrs....She went to some nearby doctor who gave her Loading dose in view of ACS...This history was not revealed in hospital...So in ED, the patient was agn given loading dose and was suspected of having acute LVF and was put on Bipap...In the morning, patient improved a little but strtd bleeding from angle of mouth....A history of small gastric ulcer was revealed (3 yrs back)...Vitals were 200/100 mmHg , PR- 90, at presentation....In morning, BP- 140/80 PR- 88/min....Discuss the treatment approach to this patient....
Dr. Hardik Ahuja2 Likes18 Answers