Discribe the antomy and functions of the neurotransmitter acetylcholine( ACh)


CONCLUSION. Thanks for the answer. Acetylcholine is synthesized from acetyl coenzyme A and choline by enzyme choline acetyltransferase. All PHERIPHERAL SYNAPSES , ACh act as the principal neurotransmitter of * Motorneuron innervating started muscle * Preganglionic autonomic neurons innervating ganglia * Post ganglionic parasympathetic neurons * Sympathetic sudomotor fibers. The functions of CENTRAL CHOLINERGIC SYNAPSES are generally less well defind than at peripheral synapses.Centeal cholinergic pathways or nuclei include *Pedunculopontine nuclei ( modulation of sleep states) * Projections to neocortex from basal forebrain nuclei( particularly the nucleus basalis of Meynett,which is thought to be involved early in Alzheimer's disease) * Local interneurons in the striatum( regulation of motor activity).

Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals (and humans) as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells, such as neurons, muscle cells and gland cells. Its name is derived from its chemical structure: It is an ester of acetic acid and choline. Parts in the body that use or are affected by acetylcholine are referred to as cholinergic. Substances that interfere with acetylcholine activity are called anticholinergics..

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