Dosage of Propylthiouracil for hyperthyroidism in pregnancy?

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Intial dose is 300 mg daily in divided dose. The pt should be informed about potential risk to mother and fetus during pregnancy. Liver function should be assessed before and after treatment with PTU . Dose may increased upto 600 mg . CBC should be done to assess agranulocytosis . Maintenance dose is 150 mg. ( Informed consent should be taken). Require opinion of endocrinologist

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