DUPUYTRENE' S CONTRACTURE

Good morning dear friends and colleagues, Today let's have a look at DUPUYTRENE'S CONTRACTURE of hand. It is one of the musculoskeletal complications of diabetes and seen in 5% of patients with diabetes. With regards, Dr Sepuri Tirumala Devi.

(Edited)

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Excellent information on Dupuytren's contracture,madam

Thanks Dr Suvarchala
1

Good informative. Is it reversible? Cause ? Neuropathy?

Thanks Dr Vasundhara. It is irreversible ,progressive and , permanent contracture of involved fingers. It is not related to neuropathy. Cause in diabetes are 1 Not exactly known. Increased prevalence of this is proportional to the duration of diabetes. 2 Localised ischemia and subsequent release of xanthine oxidase derived free radicle formation from endothelial cells. 3 pathophysiology of this is similar to wound healing like fibroblast proliferation, collagen deposition, and myofibroblast contraction driven by various growth factors .
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The common cause of Dupuytrene's contracture is supposed to be due to occupational ,or due to chronic frequent trauma.

Thank you doctor
0

excellent & useful informative

Thanks Dr Himansushekhar Nath
1

Nice info mam

Thanks Dr Viral
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Thanks mam for sharing

Very useful information mam, this type of contracture develops in what percentage of diabetic patient and is there any associated features with it.

Thanks Dr Mahesh please go through the post ,you will find the answer
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Thanks for sharing!

Welcome Dr Sameer
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Impressivecollostridial injection

Thank you doctor
0

Very nice information.

Thanks Dr Aditya
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