EYE PICTURE FOR COMMENTS

A 54 yr old with the c/o ulcers & burning sensation in the mouth for 6 months. She gave a history of vesicle formation and difficulty in swallowing food since 1 month. She also gave history of difficulty in completely opening both yes since 6 months. On general physical examination, reduced eye opening noted in both the eyes, left being more affected than the right eye. On intraoral examination, a solitary intact vesicle measuring about 5 mm in diameter was present on the lower labial mucosa, multiple intact vesicles 8–10 in number, size ranging from 4–6 mm in diameter were noted on the hard and soft palate with multiple erosive areas. Extensive shallow ulcerative areas were noted on the tongue, right buccal mucosa and upper labial mucosa. What are the differentials for this case?

A case of achondroplasia.it is a variety of short limb dwarfism.the average hight is around 4 ft. There is midface retrusion and frontal bossing. They may also have kyphoscoliosis.the hand is trident and spatulated, all the fingers are of same length.They are of normal intelligence.

what may be the diagnosis??can anyone help please.

a child came yesterday,there is hearing loss in left ear & some hypopigmentation in the neck also present, Diagnosis???

Female 2kg delivered normally at term without any significant maternal history.mother age is 40 years having 4 children all r normal. This baby is tachypnic and maintaining saturation at minimal oxygen.neonate has micrognathia rounded eyes left microtia grade 2 almost and right sided is grade 3.there is murmur which is pansystolic. Other systemic review is unremarkable  Ur opinion Plz