FERRITIN LEVELS IN COVID 19 PATIENTS

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Yes - Ferritin is an acute phase reactant besides CRP and D- Dimer .........Recent studies by Italian scientists have shown that ferritin is able to activate macrophages. The latter are a type of white blood cell of the immune system that play a critical role in innate immunity, being the body's first line of defence. This is evidenced by hyperferritinemia in patients with septic shock, catastrophic antiphospholipid syndrome, and other medical conditions characterised by macrophage activation. Similar observations have been reported by scientists from China and the United States. When activated, macrophages begin to secrete cytokines. These are a category of signalling molecules that mediate and regulate immunity. At low concentrations, they are safe for the body and help to protect it against viruses and bacteria. At high levels, the so called "cytokine storm" develops, which can be lethal for half of the patients, especially for the elderly,' explains Yehuda Shoenfeld. 'Thus, hyperferritinemia has been associated with increased illness severity and adverse outcomes, including COVID-19. Our task is to find a way to combat it.'

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Yes definately higher serum ferttin level indicates severity and seiousness of covid 19 infection.mortality is more in hyperfertinic pt.it is directly associated with viral and bactarial load in serum.

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High ferritine levels in covid19 indicates cytokine strom with increasing D-dimer As covid19 attacking coagulability and leading to DIC

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Yes, higher serum ferritin level increases severity and seriousness of COVID 19 Infection. Mortality rate is high in hyperferfftinic pt. As covid 19 Infection attacking coagulability and leading to DIC.

Yes, it does. Ferritin is an acute phase reactant. Higher levels indicate higher levels of inflammatory response to infection. Along with CRP, this can also predict cytokine storm .

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Higher ferritin level is directly proportional to severity in covid 19

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