Guide me for usage of Lubiprostone, Linaclotide & tegaserod in treatment of IBS-C?

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IBS may be a/w hardening of stools ie constipation or frequent semisolid or loose stools Always balancing of electrolytes and fluid is important for consistency of stool Yes both drugs explained are useful in IBS with hard stools Linaclotide increases sympathomimetic action and do have drowsiness

Thanx dr Pushkar ji Bhomia
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LUBIPROSTONE .. USEFUL.. IN CHRONIC.. IDIOPATHIC.. CONSTIPATION.. ASSOCIATED..WITH.. IBS .. IT WORKS WITH.. INCREASING FLUIDS SECRETION INTO .. GIT .. THERE BY .. HELPS IN STOOL SHOFTENING .. TEGASEROD .. IS USED IN.. WOMEN.. LESS THAN 65 YRS OF AGE.. FOR.. CONSTIPATION AND IBS..

Tnx Dr Shivraj Agarwal sir
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Lubiprostone is now available in India by Sun Pharma. 8mcg variant. Dosage is upto 24mcg twice daily. All these can be good choice for IBS... but avoid if patient is having obstruction or colitis.

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GI fluid balancing causing release in mechanism of constipation so that soften the stool consistency.

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Lubiprostone is also used to treat irritable bowel syndrome with constipation (IBS-C; a condition that causes stomach pain or cramps, bloating, and infrequent or difficult passage of stools) in women who are at least 18 years of age. Linaclotide is an efficacious, well-tolerated treatment option for adults with irritable bowel syndrome with constipation (IBS–C) and chronic idiopathic constipation (CIC). This medication improves both bowel symptoms and abdominal pain and discomfort. Overall, data reveal that tegaserod is an effective treatment for IBS-C, providing statistically significant relief of overall and multiple individual IBS-C symptoms (abdominal pain/discomfort, bloating, and constipation) in both placebo-controlled and “real-life” open-label settings

Lubipeostone reliev constipation Can be used in ibs

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Both are useful in constipation associated with ibs .

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ageee with @Kute Ankush in ayurved, Panchsakar powder, Triphala powder Arand bhrishtha haritak.... are useful in constipation... shunthi dhanyak fant helpful in IBS

Both are equally good

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Linaclotide is not available, but lubiprostone and tegaserod is easily available

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