Hip pain

A 62 y/o male presents with left hip pain & difficulty in walking for the past 3 months. X-ray was done which shows osteolytic lesions in the hip region. CT scan shows solitary bone lesion in the hip region. Serum sIL-2R 1210/ml LDH - 271U/l. The biopsy from tumors shows diffuse large B-cell lymphoma. Advise the management for the case.

3 Likes

LikeAnswersShare

SUGGESTIVE OF DIFFUSE LARGE. B. CELL. LYMPHOMA ADVISABLE 1. 4 DRUGS. COMBINATION CHEMOTHERAPY 2. RADIOTHERAPY

Please get a PET/CT, as it will help you stage the disease. Staging is very helpful to prognosticate and select the treatment duration. DLBCL can be of two variants- ABC and GCB which have different prognosis. The pathologist should be able to provide you with the information. Also, there is something called double and triple hit DLBCL (also called high-grade B cell lymphoma) which are treated slightly differently, are very aggressive. You need to ask the pathologist for FISH to diagnose them. However, these are better managed by a medical oncologist. One needs to make sure that there is no tumor lysis or organ dysfunction ongoing. DLBCL is treatable and curable even in advanced stages. Needs aggressive treatment though

NEED'S.. ONCOLOGISTS OPINION FOR FURTHER MANAGEMENT.. CHEMOTHERAPY.. RADIOTHERAPY..

Chemotherapy for B cell lymphoma or radiotherapy.

Thanks Dr Pushkar Bhomia
0

View 2 other replies

Radiotherapy & Chemotherapy

Diseases Related to Discussion