Case of acute or chronic Hep B

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Hbsag positive with anti hbc igm positive means acute hepatitis b infection with in 6 month Hbsag positive igm anti hbc negative positive anti igg hbc Past infection Another test hbeag positive start antiviral

Send HBc IgM. If positive wait for treatment. If negative, go for viral load HBV DNA PCR. Accordingly antiviral therapy.

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NEED'S.. HBc IgM .. POSITIVE .. WAIT FOR .. RX .. NEGATIVE .. AD .. VIRAL LOAD .. AND GIVE .. ANTIVIRAL THERAPY.. ACCORDINGLY..

Protocol.. Lft.. Hbeag AntiHbe AntiHbc IgM and Total Hbeab Hbv dna.. pcr.. quantitative to assess viral load

All these markers are mandatory to evaluate acuteness or chronicity of HBV disease.. as a window period often exists in course of appearance and disappearing of seromarkers.. Best combination is.. AntiHbcIgM + Hbeab
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Go for IgG anti HBc Antiviral to be started earliest and continue for 6months or more than review Viral loads will decide doses and duration Maintenance dose may go for couple of years

IgM if positive , can go for viral load and anti HBe

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IgM has to be evaluated

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