Is ACT(artemether and Lumifentarine) safe in pregnancy 1st Trimester?

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artemether and artesunate are contraindicated in pregnancy

What to use then mam? I have read a lot of literature which says artesunate being safe esp in first Trimester. Benefits outweigh the risks. Please guide mam @Kajal Verma
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NICELY. DISCUSSED IN. DETAILS ADVISABLE AS. AN. ADDITIONAL ANTMALARIAL. IN. SECOND. AND THIRD. TRIMESTER IN UNCOMPLICATED. PREGNANCY

During the first trimester of pregnancy, mefloquine or quinine plus clindamycin should be used as treatment; however, when neither of these options is available, artemether-lumefantrine should be considered.

Contraindicated

Thanks Dr.Dinesh Gupta, Dr. Parvez Alam
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Not safe

NOT SAFE .. SOS .. IF NO OPTIONS .. MEFLOQUINE .. SHOULD BE USED ..

Better to avoid such combination.

Shouldn't use If no other option you can use Warning by FDA

No ..

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