Is there any role of mannitol in HIE ??

1 Like


In Hypoxic Ischemic Encephalopathy , Mannitol reduces cerebral oedema which can cause hypoxic-ischemic brain damage. Not only did mannitol decrease the extent of swelling in the cerebral hemisphere undergoing tissue injury, but the drug also decreased the water content of the non- ischemic, contralateral hemisphere to a similar extent. Despite the reduction in cerebral edema, mannitol therapy was not associated with any ame- lioration in either the distribution or other way.

Role of manitol is to reduce cerebral oedema I agree with dr pharmacokinetics explained by dr Dineshchandra Sharma

Mannitol alleviate cerbral oedema

I agree with Dr Dinesh Chandra Sharma

Diseases Related to Discussion

Cases that would interest you