I need a help to understand - Is their any clinical significance of the following two verses in respect to curing the Khalitya -- which is a burning problem now a days...
KESHA ARE PITRAJA BHAAVA –
केशश्मश्रुनखलोमदन्तास्थिसिरास्नायुधमन्यः शुक्रं चेति (पितृजानि)||७|| - CHARAKA SHARIRA 3
KESHA IS A PRITHAVI PRADHAANA ANGA -
नखास्थिदन्तमांसचर्मवर्चःकेशश्मश्रुलोमकण्डरादि तत् पार्थिवं गन्धो घ्राणं च; - CHARAK SHARIRA 7/16
Hair dermal papilla cells are specialized mesenchymal cells that exist in the dermal papilla located at the bottom of hair follicles. These cells play pivotal roles in hair formation, growth, and cycling. Hair follicle formation is usually directed by an aggregation of dermal mesenchymal cells, the origin of dermal papilla cells, in the embryonic skin. We noticed that cultured dermal papilla cells also have hair-forming activity and do not lose the activity even after long-term cultivation, if they are cultured with conditioned medium from keratinocytes obtained from the sole or with a medium containing fibroblast growth factor. The secreted factors from keratinocytes and fibroblast growth factor are, therefore, important for maintaining the cellular properties of dermal papilla cells. Even if the hair bulb, including the hair matrix and the dermal papilla, has been removed from vibrissal follicles in vivo, the new hair matrix and papilla can regenerate from the rest of the follicle, and eventually a hair shaft regrows. It has been reported that hair bulb regeneration does not occur when the lower half of a hair follicle is removed. However, new hair bulbs were formed in the remaining upper halves of vibrissal follicles if the amputated follicles had been implanted under the kidney capsule. The formed bulbs were small and pelage-type, not large vibrissa-type. Histological studies showed that the new dermal papillae were derived from dermal sheath cells surrounding upper follicular epidermis, and the new hair matrices were produced from the follicular epidermis. Moreover, the upper halves of vibrissal follicles reformed large vibrissa-type bulbs when they were associated with dermal papillae or cultured papilla cells and implanted in the kidney. Thus, dermal papilla cells and probably dermal sheath cells have the ability to induce and form hair bulbs under preferred environmental conditions. Attempts to identify the genes and proteins associated with hair-forming activity of dermal papilla cells have been carried out. We and other groups successfully isolated the molecules that were specifically expressed in dermal papilla cells. The nature of the hair-producing factors could be understood through the studies of these molecules.
It's keratin , protein , present in hair , help in structural growth. Protein is paarthiva ansha predominant , therefore , most of treatment of khaalitya is with medicated oil / ghrita..
Hair loss, premature aging of hair, and thinning of hair are all signs of keratin deficiency. Although it effects numerous parts of your body like your hair, nails, etc, keratin deficiency shows most prominently on your skin. When you skin lacks keratin, it becomes pore prone to sagging, loosing its glow and wrinkles. Eating foods that increase keratin production can help alleviate this problem and help keep your skin and hair healthy for anti aging!
Here are foods for increasing keratin production to include in your keratin and skin care diet:
Fruit and Vegetables
It isn’t a surprise that foods that increase keratin production include fruits and veggies! Fruits and vegetables that are high in vitamin A aid the body in keratin production. A good indication of the nutrient content of fruits and veggies is found in their color. Produce that is orange, such as mangoes, carrots, sweet potatoes, and cantaloupe are high in carotene, which helps your body produce keratin. Carotene can also be found in spinach, green peppers, and squash.
Meat and Dairy
Iron-rich protein can boost the production of keratin in the body and improve the health of skin, hair and nails. Liver, fish and lean meats build keratin in your body. Always choose lean meat sources over red, fatty meats. Low-fat dairy, such as certain cheeses, yogurt and low-fat milk, also contain amino acids that increase keratin levels.
Their are a number of supplements on the market that stimulate growth of hair, skin, and nails. Before deciding if you should supplement your daily keratin intake, consult a physician. Overproduction of keratin or any protein in the body can be toxic and have adverse effects on the kidneys.
Iron Rich Foods
Consume iron-rich food. Iron helps red blood cells transport oxygen to your hair follicles, as well as to the other tissues that benefit from iron. Animal protein provides iron that is easily absorbed by the body. Iron-rich animal protein includes turkey, duck, chicken, pork, shrimp, eggs, lean beef and lamb. Plant foods that contain iron-rich protein include beans, spinach, black-eyed peas, soybeans, tofu and lentils.
Eat foods with plenty of vitamin C. Vitamin C enhances the absorption of vegetarian-based iron, so consume vitamin C foods at the same time that you eat vegetable-based protein. Foods rich in vitamin C include broccoli, Brussels sprouts, kale, peppers, guava, papaya, grapefruit, oranges, pineapple, strawberries and lemons. The vitamin C antioxidant vitamin for hair and skin by LifeCell is a good option to take to boost hair growth and skin, hair and nail health.
Boost your intake of B vitamins. The B vitamins enhance creation of red blood cells, which in turn carry nutrients and oxygen to your scalp, follicles and growing hair. Foods with vitamin B-6 or B-12 include wild salmon, trout, shellfish, white potatoes with the skin, bananas, lentils, garbanzo beans, fortified whole-grain cereals, lean beef, chicken breasts and pork tenderloin. Foods with folate include oatmeal, fortified whole-grain cereal, spinach, beets, parsnips, broccoli, okra, black-eye peas and soybeans.
Consume foods with zinc, such as oysters, crab, pork tenderloin, turkey, veal, chicken, peanut butter, wheat germ and chickpeas. Zinc facilitates hair and tissue growth and repair and helps maintain the oil glands that surround hair follicles.
Use keratin formulated shampoos to nourish and supplement the keratin in your hair. Keratin shampoos help repair damaged hair, protect against further breakage and add elasticity and shine. Keratin treatments, available at salons and also for home treatment, use high temperature flat irons to make the keratin bond more effectively with your hair.
Dihydrotestestrone n collagen formation is one factor responsible for hair loss.
Testosterone is the most important androgen. Testosterone production starts from adrenarche in both sexes: in males in the testes, in females in the ovaries and in both sexes to a lesser part in the adrenal cortex, too. Circulating in blood certain amounts of testosterone are bonded to Sexual Hormone Binding Globulin (SHBG). The free part represents the active steroid affecting various organs to a certain extent. Testosterone is responsible for the formation of the male-phenotype, development of muscular tissue, bone density, and in a certain way it influences the fat/sugar metabolism. It also has a big impact on skin, skin appendages, and hair in particular. Testosterone increases sebum production (seborrhoea) and controls hair growth as well as hair loss in certain areas of the body..
By:-vd.satyendra ojha sir