Low dose Mineralocorticoid receptor antagonists (Spiron- 12.5/25) given along with SGLT2 Inhibitors?
Possibility of elevation in S.Pottasium level. .And SGLT 2 can in rare case cause reduce S.Sodium and electrolyte. To keep this in mind. Better option is MRA..
MRA CAN USED
Combination of drugs causes Hyperkaelemia Benefit is their in hypertension & heart failure
MRAcan be used
I usually avoid torsemide, furosemide etc with SGLT 2. Let me know your experiences with MRA with SGLT2, as MRA is a diuretic too.
Can be given with potassium binder
Cases that would interest you
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75year old Male Ex smoker and Ex alcoholic c/o DOE *2months, loss of appetite, weakness sleepiness and palpitations o/e B. P 110/70,PR 115-120/min,SPo2-95% without O2 Chest B/L decreased air entry lower zones no Rohnchi P/A Soft and Non Tender Echo ECG Chest X-ray attached CBC TLC 16400,ESR 66 RFT normal Lft Normal pleural fluid send to lab for examination suggest diagnose and treatment
Dr. Rahul Sharma3 Likes23 Answers - Login to View the image
A 60 yr old male who is a chronic smoker presented with Breathlessness, pedal edema , poor oral intake and personality changes since 5 days....vitals at presentation were BP-160/100 PR-106/min, spO2-85%, Rbs- 88....No h/o any comorbidity..comment on the approach to this patient...
Dr. Hardik Ahuja6 Likes29 Answers - Login to View the image
43 yrs old female pt admitted with the complaints of breathlessness and palpitation. ..One day duration. . 1..ECG findings? 2..Most probable clinical diagnosis? 3..appropriate treatment? plz share your views .....Thanks in advance. .
Dr. Suresh Narayanan9 Likes33 Answers - Login to View the image
Male pt. , 40 yr , on treatment with spironolactone Dx ?
Kunjit Joshi5 Likes47 Answers - Login to View the image
33 week amenorrhea with sudden onset of severe breathlessness , EF 40,%, myocarditis , no CAD , no history of any comorbidity , BP 130/90, Pulse 120 , Respiratory rate 40 , gasping , intubated and shifted to icu On vent. please interpret the ABG. how to proceed
Dr. Naveen Arichwal1 Like20 Answers