OMALIZUMAB for parentral use specifically for chr allergic rhinitis or urticaria . Cauiously used as per body eight independent of IgE levels Quite common and precursors 9f chr allergic asthmatics In combination of Mepolizumab for asthmatics Remember not for spasmodic asthmatics it is not helpful So far steroids are concerned not out of line of treatment only decreased doses and early withdrawal is possible with this new regime. Adverse reactions are more or less like allergic symptoms only but some severe and rare cases 9f fractures are reported hence one should keep in mind while using it.
Omalizumab is definitely showing good results in severe allergic asthma But india is a poor country- at least I cannot prescribe 300 mg every 14 days as cost of 150 mg is 13000 Rupees and 300 mg will cost 26000 Rupees . A poor person cannot afford such costly medicine - these patients we are forced to put on Fexofenadine- montelukast-+ doxophylline along with salmeterol and budesonide inhaler or nebulization .
I agree with both dr Shivraj Agarwal and Dr Parveen Yograj because I want to convey the same about drug which was discussed in details by my colleagues.
I am agree @ Dr.Shivraj Agwarwal Sir ji & Dr. Praveen Yograj Sir Ji....
I am agree with@Dr. Shivraj Agarwal Sir.
Valuable suggestions thanks
Nice information thanks
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Godanti Bhasma – Benefits, Dosage, Ingredients, Side Effects Godanti Bhasma is an Ayurvedic medicine, prepared from Gypsum. It is used in Ayurvedic treatment of headache, Chronic Fever, leucorrhea etc. This medicine should only be taken strictly under medical supervision. Appearance: It is found in white colour and appears like the teeth (danta) of the cow (Go), when a stroke is given over the plaques of Gypsum. Chemically it is known as ‘Dihydrate of Calcium sulphate’. Its Chemical formula is CaSO 4 . 2H 2 o. Plaster of paris is a product prepared from it. Features of Good variety of Godanti (Gypsum): The godanti found in shiny layers is expected for medicinal purpose. It should possess crystal white colour and lustrous radiance like the moon of autumn season (Sharath ritu). According to Ayurveda , it should be purified before its acceptance for therapeutic purposes. Qualities of Godanti bhasma: Godanti bhsama is cold in nature. So, it is preferred in the treatment of Pitta imbalance disorders. Especially in jaundice, urticaia rashes, fever etc it is of proven efficacy. Because of its coolant properties, it is used in fever with high body temperature, associated with headache. Godanti Bhasma Uses: It is used in the treatment of leucorrhoea, Fever due to Pitta imbalance, Chronic fever, cough, cold, asthma, anemia, chest injury, emaciation and wasting in children. It improves strength and immunity. It is used in the treatment of migraine. Effect on Tridosha – Balances all the three Doshas, especially Pitta Dosha. Godanti Bhasma dosage: General Dose: 125 to 375 mg 250 mg once or twice a day before or after food or as directed by Ayurvedic doctor. It is traditionally administered along with ghee, honey milk or with sugar. Dose based on age: 1 – 5 years – 100 – 250 mg, in divided doses per day. 5- 16 years – 250 – 500 mg, in divided doses per day. Adults – 250 – 1 gram in divided doses per day. Purification of Godanti – Godanti Shodhana Good kind of Godanti is taken and tied in a cloth and a bundle is made. It is swinged in a pot (dolayantra) and subjected for Swedana (sudation) in the media of fresh juice of lemon or leaf juice of Leuacas cephalotus – Dronapushpi Patra swarasa, for a period of one and a half hour. Inceneration – Godanti Marana Purified plaques of Godanti are pounded and placed in between the earthen discs(plates).After proper sealing , it is subjected to heat, by using cow dung cakes. It can be kept over the gas stove as it needs moderate heat (150 0 – 250 0 C) for 1- 2 hour. When it is cooled, white colour powder is collected. This triturated well and stored. If the bhasma has not attained the fineness, once again it is subjected to heat. Godanti Bhasm side effects: This medicine should only be taken under strict medical supervision. Self medication with this medicine may prove to be dangerous. Over-dosage may cause severe side effects including gastritis, liver complicationsetc. Take this medicine in precise dose and for limited period of time, as advised by doctor. Keep out of reach and sight of children. Store in a dry cool place. How long can it be used? It is best to limit administration of Godanti Bhasma to 30 – 45 days only. Children, pregnancy and lactation: It is best avoided during pregnancy and infants. It can be administered in lower doses in lactating mother and children. But for this, direct consultation with an Ayurveda doctor is necessary. Godanti Bhasm ingredients, preparation: Shuddha Godanti – Purified Gypsum – 100 g. Purified Gypsum is triturated with aloe vera juice or lemon juice , thin cakes are prepared and heated in a closed container under 300 – 500 degree celcius to obtain Red coloured Godanti Bhasma. Different usage methods of Godanti: In case of Chronic fever it is administered along with the decoction of Guduchi ( Tinospora cordifolia) or neem. In breathlessness /asthma, the decoction of Dashamoola can be used with Godanti bhasma. Decoction of Kantakari (Solanum xanthocarpum) is effective in case of chronic cold ,cough and rhinitis followed with the medicine. It provides good body strength and promotes the appetite. Reference: Rasa Tarangini 11/241 Ayurvedic classical literatures like Rasatarangini & Rasaratna samucchaya explain the noble qualities of Godanti in detail. Manufacturers: Divya Pharmacy, Shree Dhootapapeshwar Ltd. Divya Pharmacy calls this same product as Divya Godanti Bhasma Ayurvedic medicine list with Godanti Bhasma as ingredient: Femiplex Tablet – manufactured by Charak Pharmaceuticals. Femiplex Tablet is the silver coated natural vaginal astringent. It is used for the treatment of recurrent vaginitis and leucorrhoea. Shankha Dravaka Anjal tablet – used for the treatment of fever and headache. Point capsule My experience with this formulation – Dr MS Krishnamurty: Godanti for Peri menopausal syndrome: My personal way of preparation of Godanti bhasma to obtain the benefits in case of menopausal syndrome: After obtaining the bhasma by classical method, it is further triturated with the fine paste of white coloured hibiscus flower in the ratio of 2:1.This is made in to pellets and subjected to heat. Grey or light brown coloured bhasma is obtained. It is very effective against menopausal syndrome and its complications. Especially hot flesh , dryness of body etc are relieved soon by this. Read more about perimenopausal syndrome Godanti Basm for leucorrhea: In case of leucorrhoea, fatigue, excess perspiration etc, this is administered along with yastimadhu (Glyccirrhiza glabra) and sugarcandy in 1:2:2 ratio. Read more about Ayurvedic treatment of leucorrhea – white discharge In case of heavy periods – menorrhagia, it is administered along with AshokarishtDr. Tapan Kumar Sau13 Likes27 Answers
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44 yr old lady suffering with this type of eruptions since one year.more itchy,even disturbing the sleep,n leaving black discoloration. cold weather bothers her with breathlessness can't tolerate heat more desires non veg urine..burning micturition attained menopause plz help me in diagnosis..Dr. P.varshini Krishna2 Likes27 Answers
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DERMOGRAPHISM It is an exaggerated wealing tendency when the skin is stroked. It is the commonest form of physical urticaria. It is also called dermatographic urticaria. Stroking of the skin produces a white line, then a red line, then slight swelling down the line of the stroke, and a mild red flare in the surrounding skin. In 5% of the population this response is exaggerated enough to be called dermographism. most of the cases are asymptomatic. In a minority of people it is accompanied by itching called.. symptomatic dermographism. CAUSE.. The exact cause is unknown. Histamine is the main chemical released by mast cells but other chemical mediators may also be involved. Some patients with severe dermographism may have an antibody in their serum. Occasionally dermographism is triggered by an allergy to some external agent such as penicillin, scabies or a worm infestation. Approximately 75% of patients with hypereosinophilic syndrome have dermographism. CLINICAL FEATURES.. Dermographism is most common in young adults. The onset is usually gradual. Occasionally patients may have thyroid disease. It may be related to agitation and worrying situations leading to recurrent itching. Symptoms are often worse in hot conditions, for example, after a warm bath. Minor pressure even from clothing or toweling after bath may start up the weals. At times deep extension of the swelling may occur and giant weals develop. But usually clear after half to one hour. Dermographism can occur with other types of urticaria including those due to cold or pressure. Dermographism may last for months or go on indefinitely. In many patients the severity of the problem diminish. TREATMENT H1 antihistamines are the drugs of choice. In some patients, a combination of 2 or more antihistamines may be required. Sedating antihistamines such as hydroxyzine can be helpful. Regular treatment may have to be continued for several months Omalizumab, a recombinant humanized monoclonal antibody against IgE has been successfully used in patients with physical urticaria, including symptomatic dermographism. PHOTOTHERAPY Narrowband ultraviolet (UV)-B phototherapy and oral psoralen plus UV-A light therapy have both been used as treatments for symptomatic dermographism. But the improvement is short-lived, and most patients relapse within 2-3 months of completing phototherapy. I hope this interesting topic will be useful to most of us Thanks Dr K N PoddarDr. K N Poddar19 Likes22 Answers
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18 years old girl with such skin lesions ,mild itching, painful spreading in nature. subsided after antifungal therapy ( terbinafine) but recurrent. diagnosis and treatment....Dr. S M Sarfaraj1 Like32 Answers
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Friends today I am discussing about a very serious problem most of the peoples have on change of weather. As weather is changing in these days here value of the content is important. Topic is Allergic bronchitis. Bronchitis is an inflammation in the lining of the bronchial tubes. These tubes in the lung carry air into the lungs from the mouth and nose. The swelling narrows the airway causing a cough and may make breathing more difficult. The irritation can also lead to increased production of mucus, which blocks the airway. Bronchitis can be classified as either allergic, non-allergic, or asthmatic, depending on its cause. Although the symptoms of bronchitis are similar regardless of the cause, there may also be differences, especially in how long a person will feel the effects of the condition. What is allergic bronchitis? Allergic bronchitis Allergic bronchitis occurs when an allergen inflamed the lining of the bronchial tubes. Allergic bronchitis involves inflammation of the bronchi caused by an allergen, or something to which you are allergic. Airway irritants, such as pollen, dust, and mold, can trigger symptoms. Cigarette smoking almost always causes allergic bronchitis. The symptoms of allergic bronchitis may last for a long time or keep recurring. Allergic bronchitis that lasts longer than three months is often called chronic bronchitis. This is a type of chronic obstructive pulmonary disease (COPD). Chronic bronchitis is almost always caused by cigarette smoking. Symptoms of allergic bronchitis include: a cough that produces mucus wheezing chest tightness tiredness Bronchitis can also lead to complications. For example, lung infection, such as pneumonia, can occur. In the most severe cases, pneumonia can lead to an infection in the bloodstream called septicemia. Septicemia is often life-threatening. Chronic obstructive pulmonary disease (COPD) Chronic obstructive pulmonary disease (COPD) Click here to learn more about COPD. READ NOW Non-allergic bronchitis Non-allergic bronchitis occurs because of a viral or bacterial infection. For example, some people develop non-allergic bronchitis after a cold. Although anyone can develop non-allergic bronchitis, older adults have a higher risk of experiencing the condition. People with weakened immune systems and those who smoke also have a higher chance of developing bronchitis after an upper airway infection. Symptoms often improve within a few weeks and are less likely to recur than the symptoms of allergic bronchitis. Non-allergic bronchitis is sometimes called acute bronchitis, as symptoms may onset suddenly and are typically brief. Symptoms of non-allergic bronchitis might include: a cough that produces mucus chills fever What is asthmatic bronchitis? Asthmatic bronchitis Asthmatic bronchitis can occur in people who already have asthma as an underlying condition. Like bronchitis, asthma is a lung condition that can cause breathing difficulties. Asthma can also cause inflammation of the bronchi, but can also lead to narrowing of the muscles around the airways. When bronchitis and asthma occur together, and symptoms overlap, the condition is often known as asthmatic bronchitis. Inflammation that triggers symptoms of asthmatic bronchitis might occur in someone who has underlying asthma after exposure to certain substances, such as pollen, pollution, and cigarette smoke. Some people also develop asthmatic bronchitis because of a change in weather or exercise routine. People with asthmatic bronchitis respond to these environmental triggers by releasing leukotrienes. These are inflammatory molecules. Leukotrienes cause a series of reactions, including narrowing of the airway. Symptoms of asthmatic bronchitis may include: coughing excess mucus production wheezing shortness of breath Diagnosis A doctor will diagnose allergic bronchitis based on several factors. They will review the medical history of the individual with suspected allergic bronchitis, as well as perform a physical exam, usually ask questions to determine how long symptoms have been occurring. The physician may use a chest X-ray to rule out some other causes of breathing problems, such as pneumonia. They may also request blood tests to help determine if an infection is present. The patient may also receive a pulmonary function test. This involves the individual blowing into a special device called a spirometer. The device measures how much air a person can exhale, and how quickly. The test helps doctors to identify the presence of lung diseases, such as asthma and chronic bronchitis. Treatment Treatments for allergic and asthmatic bronchitis are often similar and may include the following: Bronchodilators Bronchodilators are medications that relax the muscles around the airways. As the muscles relax, the airways dilate or widen, often making breathing easier. People take bronchodilators through a metered dose inhaler. Both short-acting and long-acting bronchodilators are available. Short-acting bronchodilators act quickly to decrease symptoms, but the effects do not last. Long-acting bronchodilators do not reduce symptoms as quickly but control symptoms for a longer period. Steroids Steroids may also be used to treat allergic bronchitis. Steroids decrease inflammation in the bronchi. This action reduces coughing and may help air-flow in the lungs. Although steroids can be an intravenous or oral medication, a physician will often administer them through an inhaler in cases of bronchitis. This allows for quicker and more effective delivery of the drugs to the area that requires treatment. Mucolytics A mucolytic drug is a medication that makes the mucus thinner and less sticky. This making it easier to expel mucus from the lungs by coughing. People can take mucolytics either orally or through a nebulizer. A nebulizer is a device that changes a liquid medication into an aerosol. A person can then inhale this aerosol. Oxygen therapy In some instances, allergic bronchitis can interfere with the efficiency of oxygen flow into and out of the lungs. People with severe allergic bronchitis may have decreased levels of oxygen in the blood. If oxygen levels are low, a doctor may prescribe oxygen therapy. This can help restore oxygen levels to normal. Pulmonary rehabilitation classes People with chronic allergic bronchitis may benefit from pulmonary rehabilitation classes. Pulmonary rehabilitation classes involve supervised exercise, along with education on how to breathe better and manage allergic bronchitis. These classes show people how to decrease exposure to allergens that may trigger symptoms. Acute non-allergic bronchitis often does not require treatment. Doctors treat asthmatic bronchitis in a similar way to allergic bronchitis, with bronchodilators, steroids, and oxygen as needed. However, acute non-allergic bronchitis may also be treated with antibiotics if caused by a bacterial infection, though this is uncommon. In some cases, a doctor may also prescribe leukotriene modifiers to treat asthmatic bronchitis. These work by interfering with the chemical reactions that cause the symptoms of asthmatic bronchitis. Home remedies humidifier A humidifier can moisten the air and loosen mucus. Many of the treatments for allergic bronchitis require a prescription. However, there are also steps a person can take at home to reduce the effects of bronchitis. Although home remedies will not cure the underlying cause of allergic bronchitis, they may help to reduce symptoms. These steps including: Using a humidifier: A humidifier will moisten the air. This can loosen mucus and make it easier to expel. It may also decrease wheezing. People with asthma should check with their doctor before using a humidifier. Drinking plenty of fluids: Drinking enough water may help keep mucus thin. Gargling with salt water: The coughing from allergic bronchitis can lead to a sore throat. Gargling with salt water might ease discomfort. Taking a cough drop: A cough drop may keep the throat moist and can provide relief from coughing. Click here to choose online from an excellent range of humidifiers with thousands of customer reviews. Prevention Preventing allergic bronchitis usually involves avoiding irritants, such as chemical fumes, dust, and air pollution. Prevention of asthmatic bronchitis includes both avoiding triggers and managing your underlying asthma according to the plan developed with your doctor. Cigarette smoke is one of the leading causes of allergic bronchitis, so quitting smoking, or not starting at all, is one of the best ways to prevent the condition. If outdoor allergens, including pollen or mold, tend to cause allergic bronchitis, wear a mask when carrying out yard work. This might also prevent symptoms. BEST HOMEOPATHIC MEDICINES FOR ALLERGY Arsenic alb - There is thin watery discharge from the nose with burning sensation, recurrent sneezing one after another with runny nose. Burning and tearing of eyes . There is puffiness around eyes, stuffy nose. The person has an asthmatic tendency with breathing difficulties, and oppression of chest which is generally worse when he lies down. On sitting with a forward bending posture makes the patient little comfort from his asthmatic problem. There is marked wheezing sound during asthmatic affection. The asthma is worse in wet cold weather. Besides that the constitutional symptoms of arsenic alb are anxiety, restlessness, prostration, burning sensation. The anxiety that is found in Arsenic alb is intermingled with fear. The other prominent symptoms are debility, exhaustion, restlessness, with nightly aggravation. Great exhaustion after a slightest exertion. Sulphur – There is itching with redness of eyes in allergic condition. The itching is followed by burning sensation and relieved by cold application. sulphur patient is always irritable, depressed, thin and weak, but good vappetite. He is having forgetful nature, difficulties in thinking. He has many good ideas but cannot implement it. Selfish type person, no regards for others. very lazy person, not cleanness, never look after about his dressing and clothing. Don’t like to take bath. Having of skin diseases always. The skin rashes itch a lot generally in night and warm atmosphere. The person has a feeling congestion or oppression of chest in asthmatic condition.– Natrum mur – Natrum mur is generally well indicated in case of allergic condition which gives the symptoms of more itching of nose, throat, ear with recurrent sneezing one after another. The characteristic discharge from the mucous membranes is watery or thick whitish, like the white of an egg.Natrum mur patient is very sensitive in nature. Every thing he/she takes into the heart. The person is irritable in nature and when in upset does not like any body’s present or giving of any consolation.Consolation aggravated the state of the mind - the melancholy, the tearfulness, sometimes brings on anger. The Natrum mur patient is extremely emotional. The whole nervous economy is in a state of fret (visible anxious like scratching finger on her skin in worry). Completely or desperately in love brings on complaints. The natrum mur patient desire to take extra salt in his diet. Sabadilla- it has good action on mucous membrane of the nose and the lachrymal glands, producing coryza and symptoms like hay-fever. There isspasmodic sneezing one after another. symptoms of hay-fever or allergic rhinitis with itchy nose and fluent coryza. Either nostril stuffed up, inspiration through nose labored, snoring. Violent sneezing is occurred from time to time, shaking abdomen followed by lachrymation. There is runny nose with severe frontal headache and redness of eyelids. Allium Cepa Allium Cepa is one of the most commonly used Homeopathic medicines for Allergic Rhinitis or Hay Fever. It is generally used in the symptoms of severe runny nose that drips from the tip of nose with watery eyes. There is burning of nose due to over secretion mucous. Along with the watery nasal discharge there is watery eye. There is profuse sneezing associated with runny nose and watery eyes. Tuberculinum- The patient is very susceptible to catch cold. The physical constitution is lean and thin like natrum mur, but not obese like calcarea carb. If there is family history of tuberculosis or bronchial asthma then is more suitable to give this medicines in any allergic or asthma condition. The person is very depressed, melancholic, taciturn sulky nature.Dr. Rajesh Gupta16 Likes24 Answers