Quick Recall
Patient N, a 23-year-old medical student arrives in the ER with complains of difficulty in swallowing, sore throat, and chills. Upon examination, she is found to be running a fever, and has white patches on her tonsils. A throat swab is positive for Streptococcus pyogenes (group A). A diagnosis of acute pharyngitis is made. Her past medical history is unremarkable except for an anaphylactic reaction to cefaclor 2 years ago. Which of the following would be a safe alternative for treating N's condition?
- A. Oral Amoxicillin
- B. Oral Cephalexin
- C. Clindamycin
- D. Meropenem
- E. Nafcillin
SUGGESTIVE OF.. C/ ..*A*.... ALTHOUGH... CEPHALEXIN....IS THREE. TIMES. MORE. EFFECTIVE.... AND THREE. TIMES. LESS. LIKELY. TO. FAIL....IN *STREPT...... . .... THROAT / PHARYNGITIS*... BUT....SINCE... . ..THE. PATIENT. IS. SHOWING... ANAPHYLACTIC. REACTION. TO ......*CEFACLOR*........ SO.... CEPHALOSPORINS. SHOULD. BE AVOIDED... AND ALTERNATIVE....BEST. OPTION. IS... CLINDAMYCIN .... AND PENICILLIN AMOXICILLIN AMPICILLINE AMOXICLAVE
Option A is INCORRECT. Amoxicillin is a penicillin, which has a high enough risk in cross-reacting to another beta-lactam to be considered "not worth the risk" when treating a sore throat in a patient with a history of anaphylactic reaction to another type of beta-lactam antibiotic. The correct answer is, "C. Clindamycin. This is chemically different type of antibiotic (a lincosamide) that inhibts protein synthesis, and is effective against beta-lactamase producing bacteria such as group A strep." The objective of this question was for you to identify a drug that would NOT cross-react with a beta-lactam in a patient with a history of beta-lactam induced anaphylaxis.
Oral Amoxicillin
Amoxyclav better drug
MOXIKIND 625MG TWICE ADAY WITH BCOMPLEX SPOROLAC DS GARGLE WIH HOT WATER.IF NECCESSARYAND AFFORDABLE DO CULTURE AND SRNSITIVITY NOW.IF NO IMPROVEMENT RESULT WILLBE AVAILABLE
Clindamycin group best to treat pharygeal infections..
Dr Ranjit Kumar Poriya Homeopathy Option A,
Amox
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