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Amongst those antibiotics that act by inhibiting protein synthesis, several members this drug class are known to produce side effects related to both drug interactions caused by inhibition of P-450 and cardiac effects (QT prolongation/Torsade de pointes). Which drug class is this?

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SUGGESTIVE. OF ... C... CERTAIN.... MACROLIDES... LIKE CLARITHROMYCIN ERYTHROMYCIN... ARE. POTENT. INHIBITORS..OF.. CYTOCHROME P 450. SYSTEM... WITH Q - T. INTERVAL. PROLONGATION.... CAUSING... TORSADO DE POINTES..

yeah, just saw in KD TRIPATHI its macrolides
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C. MACROLIDES : azitromycine, claritromycine, erythromycin Macrolide act by inhibiting bacterial protein synthesis. Side effects qt prolongation. Inhibit P-450 , nausea, vomiting, diarrhea,

C. Macrolides like Erythromycin is the correct answer. Straightforward question.

B&C Flouroqinoline in high doses causes QT prolongation Certain Macrolides are protein inhibitors

The correct answer is, "C. Macrolides"

C.MACROLIDES

Thanks Dr Dinesh Gupta
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MACROLIDES.

C. Macrolides like Erythromycin, Azithromycin causes QT prolongation

Floroquinolons

Only macrolide Qt prolongation P450 inhibiton

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