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According to the latest research, Favipiravir in combination with Tocilizumab improves pulmonary inflammation of COVID19 patients more when compared to Favipiravir monotherapy.

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Agreed if two drugs are given in combination at earliest stage is mild symptoms of covid infection further critical stage can be avoided It helps in early discharge and less or no 02 requirement

Thanx dr Md Altaf Hussain
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YES... ...SUGGESTIVE. OF ..* A. *... TRUE. BECAUSE... IN. COMPARISON... TOCILIZUMAB ......MONOTHERAPY... IS. BETTER. THAN.... FAVIPIRAVIR. MONOTHERAPY ... TOCILIZUMAB. .... IS. EQUALLY. EFFECTIVE..... IN. COMBINATION. THERAPY ( WITH. FAVIPIRAVIR ) AND. MONOTHERAPY AS. WELL

Dear @Dr. Dinesh Gupta sir ..pls mention both drug dose per day (in mg)and duration..
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Everything depends upon the crucial timing of initiation of treatment & clinical scenario... Early & timely initiation alongwith monitoring is crucial to the response in case of Antivirals & Immunomodulators

Research is indicating towards TRUE. To early too comment still in initial stage.

Thanks dear Hussain
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True combination of both drug Lithal

Is this combination lethal?
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True Il6 high then only tocilizumab

Combination therapy will sure give better result if used before 9th days of exposure from Covid 19

The mechanism of action of Fabipirvir and Tocilizumab are totally different.Fabipiravir inhibits +ve sense mRNA replication and Tocilizumab is IL6 blocker.So Fabiflu should be in the beginning stage of covid19 patients and Tocilizumab should be given to stop cytokine storm along with steroids.Both the drugs should not be combined.So far the ideal drug to inhibit viral replication is Remdesivir 100mg IV daily over a period of 1 hour for 5 days.Viral replication starts 7 days before IL6 that acts on naive T cells to become TH 17 which increases neutrophil counts responsible for cytokine storm.

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