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Remdesivir and chloroquine when administered to a COVID-19 patient with SpO2 <94 will have synergistic beneficial effect.

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SUGGESTIVE. OF 1... ...... TRUE.... W H O. ....TRIALS. ..HAVE. SHOWN... COMBINATION. OF.. ANTIVIRAL ( REMDESIVIR ) ANTIMALARIAL( CHLOROQUINE) ANTI. HIV....(RITONAVIR/LOPINAVIR ) HAS. ..... ..EFFECTIVE ..SYNERGYSTIC AND. .. PROMISING EFFECTS.. AS. THESE. DRUGS. IN. COMBINATION.. . TARGET. DIFFERENT. STEPS. OF. VIRAL.REPLICATION....SO. THAT. ...THERE. ARE. LEAST. PROBABILITIES. OF. VIRUS. ....DEVELOPING. MUTATIONS...

Can be true. We need time from various nations to give data to compile things. We may reach to a conclusion. I feel we are in a big hurry. Let us corelate infective cure and death rates and try to find out what can be applied to all and what drug therapy should be applied to all.

Reduce effect of remdesivir concurrent use of chloroquine

It is a false statement.

Thanks Dr Dinesh Gupta
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I think - COVID-19 disease treatment should be clear cut .There should not be any confusion.as now in india we are facing peak with more than 90000 patients are coming daily and we have a tough time ahead On curofy- platform we should have clear concepts of treatment. We should not put trials on COVID-19 patients who already are immuno- compromised. Addition of chloroquine to remdesivir will do more harm than good .As remdesivir is reserved for severe - COVID-19 patients who already are immuno- compromised and chloroquine can precipitate severe gastritis. Even there are lot of side effects of remdesivir also . EVEN REMDESIVIR alone is not effective in severe COVID-19 patients. It needs to be combined with non - invasive or invasive ventilation, Dexamethasone, LMWH, supportive treatment. There is no sense on giving chloroquine to such patients Let Chloroquine be reserved for only prophylaxis of contacts . We Indians- should follow clear cut protocols for COVID-19 patients as Americans do . We should treat COVID-19 severe patients with minimal possible effective medications and only proved therapies should be given THANKS- These are my personal views. Many may differ- but let clarity be in doctors mind who are treating COVID-19 patients

The correct answer is, "False". Chloroquine reduces the effect of Remdesivir by an unknown mechanism.

Hydroxy chloroquine is a supportive medication in covid some pt have cardiac toxicity seen

It depends upon the individual patient,overall no significant synergistic benefit.

Its contraindicated in icmr guideline Both drug should not given together

Chloroquine may decrease the antiviral activity of remdesivir.

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