Razumab vs Ivta which is better for diabetes patients?
58 years patients have diabetes, already provided accentrix twice and Razumab. As accentrix and Razumab is expensive patient want to go for Ivta. What is your advice? History -Diabetes Chief Complaints Leakages of blood vessels in the eye Physical Examination BP - 149/91 Weight - 56KG
Cystoid macular edema with CNVM Ivta intravitreal triamisolone acetate In diabetic macular edema ,edema May completely resolve and visual acuity may increase as much as macular ischemia and tissue distraction by diabetic process may allow For proliferative diabetic retinopathy and neovascular glaucoma antiangiogenic effect of Razumab has to be used
Cystoid macular edema Intra vitreal avastin can be given For better evaluation and follow up reffer patient to retina specialist
Macular edema : Intravetreal Avastin injection can be given . It is effective & cheaper compared to other medicines.
IT'S A..CASE OF.. DIABETIC MACULAR OEDEMA.. NEED'S..EXPERTS OPINION..
THEY ARE NON SPECEFIC ANTI VEG AGENTS COSTLY DRUG DIES NOT HAVE ANY BENEFECIAL EFFECT
BOTH ARE NON SPECEFIC
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Interpret the FFA of a 56 year old diabetic with uncontrolles blood sugar levels and history of laser in the past.
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DIABETIC RETINOPATHY. Diabetic retinopathy is a progressive damage to the retina which occurs in diabetics.It is a serious sight- threatening complication of diabetes. Diabetic retinopathy depends on the duration of diabetes and the glycemic control. Here ,the tiny blood vessels leak blood and other fluids. SYMPTOMS. 1.Seeing spots or floaters. 2.Blurred vision. 3.Having a dark or empty spot in the centre of the vision. 4.Difficulty seeing well in the night. Long standing hyperglycemia causes fluid to accumulate in the lens that controls focussing. This changes the curvature of lens leading to blurred vision. STAGES OF DIABETIC RETINOPATHY. STAGE I : Microaneurysms occur. STAGE II : Some blood vessels that nourish the retina are blocked. STAGE III : More blood vessels are blocked, depriving several areas of retina of it's blood supply. STAGE IV : New blood vessels grow (Neo vascularization),but they are abnormal and fragile. They leak blood leading to vision loss and blindness. ANOTHER CLASSIFICATION. 1.NON-PROLIFERATIVE DIABETIC RETINOPATHY Signs of NPDR given in a mnemonic. Microsoft Dot com Rated Internet Very Cool and Definitely Hot. Micro aneurysms. Dot and blot hemorrhages. Retinal edema. Intraretinal micro vascular abnormalities. Venous abnormalities. Cotton-wool spots. Dark blot hemorrhages. Hard exudates. 2.PROLIFERATIVE RETINOPATHY. Neo vascularization of disc. Neo vascularization elsewhere in the retina Fibrovascular proliferation. Vitreous hemorrhage TREATMENT. Treatment of Diabetic retinopathy depends on the stage of disease. THE GOAL OF ANY TREATMENT IS TO SLOW OR STOP THE PROGRESSION OF THE DISEASE. PHARMAVOLOGIC THERAPY. TRIAMCINOLONE: Administered intra vitreously, corticosteroid used in the treatment of Diabetic macular edema. BEVACIZUMAB :Administered intra vitreously, monoclonal antibody that can help to reduce Diabetic macular edema and neo vascularization of disc and retina. RANIBIZUMAB : Administered intra vitreously, monoclonal antibody that can help to reduce Diabetic macular edema and neo vascularization of the disc and retina. GLYCEMIC CONTROL. Intensive glucose control is essential to slow or stop these changes. In the early stages of non-proliferative Diabetic retinopathy, regular monitoring may be the only treatment. Diet,exercise and maintaining normoglycemia helps to control the progression of the disease. In the later stages,leakage of blood through the capillaries can be reduced by LASER TREATMENT OR PHOTO COAGULATION .A laser beam of light creates small burns in the retina with abnormal blood vessels and the leaks are sealed LASER PHOTO COAGULATION IS INDICATED IN THE TREATMENT OF CLINICALLY SIGNIFICANT MACULAR EDEMA IN NDPR. PANRETINAL PHOTO COAGULATION IS USED IN THE TREATMENT OF PDR. VITRECTOMY :This is used in PDR in cases of long standing vitreous hemorrhage. CRYOTHERAPY : When laser photo coagulation in PDR is precluded in the presence of an opaque media, such as in cases of cataract or vitreous hemorrhage, cryotheapy may be applied. DIAGNOSIS. LABORATORY STUDIES OF HbA1C LEVELS ARE IMPORTANT IN THE LONG TERM FOLLOW UP CARE OF PATIENTS WITH DIABETES AND DIABETIC RETINOPATHY. FLOTESCEIN ANGIOGRAPHY. OPTICAL COHERENCE TOMOGRAPHY SCANNING B- SCAN ULTRASONOGRAPHY. PATIENT EDUCATION. THE MAINSTAY OF DIAGNOSING DIABETIC RETINOPATHY IS A COMPLETE OPHTHALMIC EXAMINATION AND DILATED RETINAL EXAMINATION BY AN OPHTHALMOLOGIST. EXCELLENT GLUCOSE CONTROL IS BENEFICIAL IN ANY STAGE OF RETINOPATHY. IT DELAYS THE ONSET AND SLOWS DOWN THE PROGRESSION OF OF THE DIABETIC COMPLICATIONS IN THE EYE. SYSTEMATIC PROBLEMS LIKE HYPERTENSION, RENAL DISEASE AND HYPERLIPIDEMIA MAY CONTRIBUTE TO DISEASE PROGRESSION. SMOKING MAY COMPROMISE OXYGEN DELIVERY TO THE RETINA. THEREFORE, ALL EFFORTS SHOULD BE MADE IN THE REDUCTION, IF NOT OUTRIGHT CESSATION OF SMOKING. VISUAL SYMPTOMS LIKE VISION CHANGES, FLOATERS,DISTORTION, REDNESS AND PAIN COULD BE MANIFESTATIONS OF DISEASE PROGRESSION AND SHOULD BE REPORTED IMMEDIATELY.
Dr. Suvarchala Pratap16 Likes8 Answers - Login to View the image
Explain this Ultrasound finding of a 56 year patient right eye with uncontrolled diabetes and dimiunition of vision since 15days. On examination vision PL+PR inaccurate. Media hazy glow present disc barely visible,fibrovasular bands emanating from the disc.
Dr. Neha Mehrotra5 Likes8 Answers - Login to View the image
Dear ophthalmologists, one of my relative underwent cataract surgery for lft eye 3 months back. now had watering from same eye. he visited the eye specialist. was explained to take weekly injection in left eye. posting the images. pl explain
Dr. Sudhir Kumar Vujhini2 Likes5 Answers - Login to View the image
40 y/o female with a PMH of type II DM, presented with worsening blurry vision in her left eye. she had h/o diabetic macular edema. Best corrected visual acuity was 20/25 in the right eye and 20/400 in the left eye. Fundus examination of the right eye revealed mildly tortuous vessels. Can you give your opinion?
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