Recurrent Glioblastoma
Chief Complaint A 63 y/o male presents with the complaint of headache. History 1 year back he came with headache for 1 month which was increased for 1 week. Examination at that time showed increased intracranial pressure. MRI showed a left temporal lesion compressing other structures. Total excision of the tumor was done with no complications. Histology showed Glioblastoma. He underwent radiotherapy and was symptom free post-operatively. His follow ups were wnl. After 1 year he again came back with a severe headache. Investigations MRI was done which shows a residual tumor at the same site. Treatment What is your advise for the patient?
Recurrent glioblastoma temporal lobe Malignant in nature Surgically removed once Now recurrence Assess the size of tumor and preferably removal again followed by chemoradiotherapy
Recurrent glioblastoma temporal lobe. Malignant in nature. Needs further evaluation and surgical intervention required followed by chemoradiotherapy. Keeping the age pts vital system and proper assessment can be considered before surgical intervention.
Recurrent Glioblastoma Already operated and received radiotherapy It's an incurable disease with poor prognosis There is nothing much that can be done Adv Palliative and best supportive care
In view of his age of 63 open skull surgery is not advisable.. Better to consult Kruti Sturgeon for recent new method of removal.
Further evaluation is required for diagnosis and treatment by an Neurosurgeon & an Oncologist
Recurrent glioblastoma has very poor prognosis. You can consult neurosurgery to see if a re resection is possible, which can happen in 20-30% patients.. If not then one can use Bevacizumab in recurrent disease however the disease control for long time is unlikely. Other chemo option including PCV provide short term benefit. There are clinical trials ongoing using combination immunotherapy, but these are very expensive and with unproven benefit yet.
Glioblastoma prognosis poor Opinion of onconeuro Pet scan
Opinion on oncosurgeon and radiation oncologist.
Recurrent tumour ? Glioblastima Surgical removal followed by chemo and radio therapy
Cases that would interest you
- Login to View the image
A young male 34 yrs old who is a Engineer by profession presented with GTCS for the first time....He was in post ictal phase during admission....MRI brain was done....What could be the possible differentials in this case and the approach to this patient
Dr. Hardik Ahuja6 Likes24 Answers - Login to View the image
A 5 yr old girl presented with severe headache and vomiting for the past 4 hours. Her mother denies any history of trauma to the head. She seems to have limp in her gait recently, mainly supporting herself with her right leg. no delay in milestones. Has anemia since age 3 years. What is your opinion? What is diagnosis for marked area?
Dr. Rajesh Hirani2 Likes21 Answers - Login to View the image
40 yr old, M , presented with progressive weakness of LT side 6 months, head ache early morning 2 months & 7 episodes of Lt focal fits lasting for 2 mts for the last 3 weeks.On exam normal optic fundi with gr3+/ 5 power with LT sided pyramidal signs. Intact sensations. What is the diagnosis?.
Dr. Manorama Rajan2 Likes25 Answers - Login to View the image
68 yr, F, No known disease in the past, investigated foe first episode of unprovoked fit, discription suggestive of Generalised tonic clonic convulsion.Denied having any loss of wt / appetite.Examination failed to obtain any focal deficits.Systemic exam was unremarkable. Rotein blood work up, xray chest US abdomen were normal Pt was already refer to neurosurgeon . What is the possible diagnosis?
Dr. Manorama Rajan0 Like18 Answers - Login to View the image
A 79-year-old woman presented with a 1-year history of gradual neurological decline involving confusion, memory loss, and imbalance. What is the most likely diagnosis? A) Colloid cyst B) Glioblastoma multiforme C) Thrombosed intracranial aneurysm D) Choroid plexus metastases E) Intraventricular meningioma
Dr. Raj Sharma4 Likes18 Answers