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22 yr female with incidental finding of raised indirect hyperbilirubinemia. Hb, RBC, pcv is low then normal limit[ 1 week back]. Patient has no symptoms of yellowing of skin or sclera, change in urine colour. No complains..... 2 week back same reports were done patient had parameters on the lower normal limit. Kindly help with Ddx, further investigation, treatment... This case was earlier though to be Gilbert syndrome ?, But in recently done additional investigation there is signs of sickling , and raised LDH ,
Dr. Md Faraz1 Like12 Answers - Login to View the image
four years male present with anasarca bilateral pitting oedema fluid thrill and shifting dullness positive umbilicus everted periorbital puffiness icterus positive hepatosplenomegaly with attached report. rk 39 and Australia antigen is negative. usg report suggestive of ascites and hepatosplenomegaly.is there possibility of autoimmune hepatitis because SGPT IS NOT MUCH ELEVSTED IN COMPARISION TO SERUM BILIRUBIN ELEVATION. HISTORY of blood TRANFUSION one time. history of casualty of sister three months ago. sister suffering from same problem according to patient father. father is migrant worker. chest X-RAYS suggestive of cardiomegaly. further investigation and treatment.
Dr. Rajeev Gupta2 Likes16 Answers - Login to View the image
A young female aged 14 years presented with complaints of jaundice (on/off), severe fatigue and weakness since 2 months....On examination she was found to have severe anemia along with Jaundice....CBC showed Pancytopenia....A diagnosis of Hemolysis was made...Comment on the clinical approach and investisgations required to treat the patient...
Dr. Hardik Ahuja2 Likes23 Answers - Login to View the image
23 year boy with c/o anemia, jaundice , splenomegaly on and off since childhood HB 13.5, TC and PLT within normal range MCV 77, MCHC 36.5, RDW 19 retic 19% ICT/DCT negative Indirect hyperbillirubinemia PS pictures for comments
Dr. Rakesh P1 Like11 Answers - Login to View the image
27 yo , male , no previously known comorbidities with complaints of yellow discoloration of sclera for 2months. Negative history -No ho fever, malaise, breathlessness , abdominal distension , pallour, pedal edema, pruritis, unprotected intercourse , needle pricks, abdominal pain , drug use, alcohol consumption , discoloration of stools or urine , or any history suggestive of encephalopathy. Past history - similar history in 2011 was received with udiliv 300 but no reports or diagnosis made. No hospital admission. On further probing , cousin told that the sclera used to be mild yellowish as long he has known him, but was exacerbated in 2011 and now. He was started on udiliv and shown improvement but on stopping meds bilirubin rose again . Fluctuatling between 2-4 g/L. The investigations ordered by us are shown Ldh levels and usg abdomen is Normal (report pic not present) Tentative Diagnosis pointing towards congenital cause (Gilberts Syndrome ? Query)
Dr. Vishal Varghese3 Likes10 Answers