Systemic Antifungals in Pregnancy

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At present, very little data exists regarding the safety of systemic Antifungals in pregnancy. Use of Griseofulvin, Ketoconazole, Voriconazole, Flucytosine and Potassium Iodide are contraindicated in pregnancy. There are serious risks of fetal malformations associated with the use these drugs.   Although it is classified under pregnancy category B, oral Terbinafine should be avoided until after delivery and even during lactation. A single dose of fluconazole 150 mg to treat vaginal yeast infection during pregnancy does not appear to be associated with the birth defects. In short all superficial fungal infection must be treated with only Local Antifungal like Micanazole. All oral Antifungal are  contraindicated and must be avoided during pregnancy.

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TERBINAFINE CAT. B shouted avoided until after del and during lactation FLuconazole single dose can be given not associated with birth defects ITRACONAZOLE CAT C Should be avoided especially in first trimester though clinical trials have not detected any risk

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Fluconazole 150mg 1 Tablets

No oral antifungal is safe during pregnancy . Topical antifngals are safe .

Apparently fluconazole 150mg single dose is safest during pregnancy

Single dose of Fluconazole is safer than remaing two options.

SINGLE DOSE OF.. FLUCONAZOLE 150MG..

But sir she is a patient of tinea corporis
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FDA approved terbinafine Only

Fluconazole

Fluconazole

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