The investigations written below, are done for?? please explain..
RETICULOCTES COUNT TO RULE OUT LEUKEMIAS , PBS TO RULE OUT SICKLE CELL ANAEMIA AND HAEMOGLOBINOELECTROPHORESIS TO RULE OUT THALASSEMIA MINOR AND THALASSEMIA MAJOR...IN THALASSEMIA MINOR HB.ELECTROPHORESIS SHOWS HBA2 INCREASES.AND SLIGHT INCREASE IN HBF...THIS IS THE CASE OF BETA THALASSEMIA MINOR. ...IN BETA THALASSEMIA MAJOR HB.PATTERN IS DIFFERENT .HERE ELECTROPHORETIC STUDY SHOWS HBF ABOUT 10 TO 98 %..HBA VERY LITTLE OR ABSENT.HBA2 IS VARIABLE . IN CASE OF THALASSEMIA ALFA TYPE HBH IS 5 TO25% .REMAINDER IS HBA, A2 AND F. BASICALLY THALASSA MEANS SEA; HAIMA ,BLOOD ..ITS A GREEK WORD . ITS A GENETICALLY TRANSMITTED HB ABNORMALITY......C.F.. ..COOLEY'S ANAEMIA........DR.RAJESHGOPAL. MBBS IMA PMC REG NO 35726.LUDHIANA.
Iron deficiency anemia Thalassemia Minor n major Sideroblastic anemia Anemia of chronic disease Hemoglobinopathies Myeloproliferative disorders Iron studies to be added for a better differential diagnosis with bone marrow exam.
Sickle cell anaemia / thalessemia / myeloproliferative disease.
Reticulocyte count, cellular morphology of Peripheral Blood Smear and Haemoglobin Electrophoresis to determine Thalassemia or Sickle cell Anaemia
reticulocyte count peripheral blood film and haemoglobin electrophoresis all these tests are used for anaemia work up. blood film gives idea about morphology of ted blood cells abnormal shape rbcs any blasts and any blood parasites. hb electrophoresis is used in diagnosis of thalassemia and sickle cell anaemia as well as m band electrophoresis for diagnosis of multiple myeloma
for diagnosis of thalassemia minor & major, sickle cell anaemia, cong. hereditary spherocytosis & elliptocytosis, sideroblastic anaemia & especially hemolytic anaemia etc.
peripheral smear picture. suggest for Hb electrophoresis to r / o thallesaemia. sickle cell anaemia. ..
to rule out Thallasemia
To rule out haemoglobinopathies
for hemoglobinopathies....
Cases that would interest you
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1 yr 6 month male child with CBC picture suggestive of hemolytic anemia and leucoerythroblastic reaction. Hb electrophoresis report is as per image..kindly guide for further investigation and diagnosis..
Dr. Rakesh Pimpaldara0 Like3 Answers - Login to View the image
Target cells in peripheral smear. Kindly give differential diagnosis?
Dr. Viraj R. Naik4 Likes22 Answers - Login to View the image
a 19 year girl was admitted in fmw with complains of fever with chills and rigor abdominal pain loose motion on examination pallor hepatosplenomegaly was present past history of same complains was present three to four times with in 6 month past history of pcod. severe hypomenorrhoea and 2 BT WAS DONE. I POSTED present cbc findings ps blood image and sickling test images......may be useful and rare to find intresting case.....give ur expert opinion thanks
Dr. Arvindra Rahul2 Likes17 Answers - Login to View the image
35 yrs male -peripheral smear and cbc your opinions
Dr. Dommeti Durga Prasad1 Like14 Answers - Login to View the image
A 35-year-old man with a history of sickle cell disease presented with a sickle cell crisis and headaches. Noncontrast computed tomography (CT) of the head revealed a thickened calvaria with perpendicular proliferation of the trabeculae, a finding termed the hair-on-end sign (Panels A and B). The hair-on-end sign was historically described on plain films (although it can also be seen on CT and magnetic resonance imaging). Name the conditions associated with the above mentioned findings ? (source: online journal)
Dr. Mohammed Parvez10 Likes6 Answers