The investigations written below, are done for?? please explain..

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RETICULOCTES COUNT TO RULE OUT LEUKEMIAS , PBS TO RULE OUT SICKLE CELL ANAEMIA AND HAEMOGLOBINOELECTROPHORESIS TO RULE OUT THALASSEMIA MINOR AND THALASSEMIA MAJOR...IN THALASSEMIA MINOR HB.ELECTROPHORESIS SHOWS HBA2 INCREASES.AND SLIGHT INCREASE IN HBF...THIS IS THE CASE OF BETA THALASSEMIA MINOR. ...IN BETA THALASSEMIA MAJOR HB.PATTERN IS DIFFERENT .HERE ELECTROPHORETIC STUDY SHOWS HBF ABOUT 10 TO 98 %..HBA VERY LITTLE OR ABSENT.HBA2 IS VARIABLE . IN CASE OF THALASSEMIA ALFA TYPE HBH IS 5 TO25% .REMAINDER IS HBA, A2 AND F. BASICALLY THALASSA MEANS SEA; HAIMA ,BLOOD ..ITS A GREEK WORD . ITS A GENETICALLY TRANSMITTED HB ABNORMALITY......C.F.. ..COOLEY'S ANAEMIA........DR.RAJESHGOPAL. MBBS IMA PMC REG NO 35726.LUDHIANA.

PRESCRIPTION WRITTEN IN THIS MEMBER ARE SOME TIME NOT UNDERSTOOD ....KINDLY WRITE CLEAR WORDS , THAT SHOULD BE UNDERSTANDABLE BY ALL AT LEAST LESS INTELLIGENT LIKE ME .... .SALUTE TO DOCTOR'S PRESCRIPTION .RAJESH GOPAL.
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Iron deficiency anemia Thalassemia Minor n major Sideroblastic anemia Anemia of chronic disease Hemoglobinopathies Myeloproliferative disorders Iron studies to be added for a better differential diagnosis with bone marrow exam.

Sickle cell anaemia / thalessemia / myeloproliferative disease.

Reticulocyte count, cellular morphology of Peripheral Blood Smear and Haemoglobin Electrophoresis to determine Thalassemia or Sickle cell Anaemia

Thanks Mam !
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reticulocyte count peripheral blood film and haemoglobin electrophoresis all these tests are used for anaemia work up. blood film gives idea about morphology of ted blood cells abnormal shape rbcs any blasts and any blood parasites. hb electrophoresis is used in diagnosis of thalassemia and sickle cell anaemia as well as m band electrophoresis for diagnosis of multiple myeloma

for diagnosis of thalassemia minor & major, sickle cell anaemia, cong. hereditary spherocytosis & elliptocytosis, sideroblastic anaemia & especially hemolytic anaemia etc.

peripheral smear picture. suggest for Hb electrophoresis to r / o thallesaemia. sickle cell anaemia. ..

to rule out Thallasemia

To rule out haemoglobinopathies

for hemoglobinopathies....

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