What is the criteria for uraemic encephalopathy?

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Uremic encephalopathy may occur in a patient with acute kidney injury or chronic kidney failure of any etiology. One contributing factor to uremic encephalopathy may involve imbalances of neurotransmitter amino acids within the brain.. Early symptoms of uremic encephalopathy include nausea, anorexia, restlessness, drowsiness, and slowing of concentration and cognitive functions. As uremic encephalopathy progresses, patients typically become more disoriented, confused, and may exhibit bizarre behavior and emotional instability.

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Uremic Encephalopathy occurs in patients with acute or chronic renal failure, once the estimated GFR (eGFR) declines and stays below 15 mL/min. It is important to recognize the signs and symptoms early, as untreated uremic encephalopathy can progress to coma, while symptoms are easily reversible with dialysis.

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